Protein Alignment CG17134 and Ren1

DIOPT Version :10

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_112469.1
• Gene: Ren1 / 19701
• MGIID: 97898
• Length: 402
• Species: Mus musculus
• Alignment Length: 327
• Identity: 146/327 - (44%)
• Similarity: 200/327 - (61%)
• Gaps: 11/327 - (3%)

  Fly    68 LHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYVANG 132
            |.|.:|.:|||.|.||||.|.|.::||||||||||||..|.....||..|:.|:||.||:|:.||
Mouse    76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENG 140

  Fly   133 EEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGILGLAFSAIAVDGV 197
            .:|.|.||:|.:.||||.|.||:.||:: .|||||....|...|:.|.|.|:||:.|.|.||.||
Mouse   141 SDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGV 204

  Fly   198 TPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVPVSVPAYWQFKVNT 262
            ||.||:::|||:|.|.|.|.|..| |:.:.|||::|||.|...|:|:..||.:|....||..:..
Mouse   205 TPVFDHILSQGVLKEEVFSVYYNR-GSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKG 268

  Fly   263 IKT-NGTLLC-NGCQAIADTGTSLIAVPLAAYRKINRQLGATDNDGEAF-VRCGRVSSLPKVNLN 324
            :.. :.|||| .||..:.|||:|.|:.|.::.:.|.:.|||.:...|.: |.|.:|.:||.::.:
Mouse   269 VSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFD 333

  Fly   325 IGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYME-----GLSFWILGDVFIGKFYTVFDKGNERIG 384
            :||..:||:..||:::........|..|...|:     | ..|:||..||.||||.||:.|.|||
Mouse   334 LGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTG-PVWVLGATFIRKFYTEFDRHNNRIG 397

  Fly   385 FA 386
            ||
Mouse   398 FA 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:472175	143/323 (44%)
Ren1	NP_112469.1	A1_Propeptide	31..>49	CDD:462326
		renin_like	76..401	CDD:133154	146/327 (45%)