Protein Alignment CG17134 and asp-18

DIOPT Version :9

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_507653.2
• Gene: asp-18 / 191310
• WormBaseID: WBGene00013973
• Length: 392
• Species: Caenorhabditis elegans
• Alignment Length: 407
• Identity: 139/407 - (34%)
• Similarity: 209/407 - (51%)
• Gaps: 50/407 - (12%)

  Fly     4 LLVLLVLVGIGHSAAKLNRVQLQVNKNFTKTHGSVKAEKTVLASKY-SFLAETSFSVSSSGATEN 67
            ||:|||..    .:|.:.:|.       |.|.||.:| |.:...|| ||||.....:::  .::.
 Worm     3 LLLLLVTT----CSAAVFQVP-------TTTSGSFRA-KLIREGKYSSFLASRLQQLNT--GSQP 53

  Fly    68 LHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQ-------RHNKYDSSAS 125
            |....::...|.|.||:|.|...:..||.||||||..::|.:.|  |.       :| |::::.|
 Worm    54 LLGFSDDPCIGNITIGSPPQSAFVFMDTTSANLWVMGSACTSVN--CNDPLLGIIKH-KFNTTKS 115

  Fly   126 STYVANGEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVD-----APFAGIL 185
            :::|.:..:|.|:||:|..||:|..|.|.|.|:.||.|.||.|      ..||     .|..||.
 Worm   116 TSFVKSNRKFNIQYGSGECSGYLGTDTVEIGGLKIQKQEFGVA------NIVDYDFGTRPIDGIF 174

  Fly   186 GLAFSAIAVDGVTPPFDNMISQGLLDEPVISFYLKRQGTAV---RGGELILGGIDSSLYRGSLTY 247
            |||:.|::||.||||..|::||..||.|:.:.:..::....   ..|.:..||:|:.....:::|
 Worm   175 GLAWPALSVDQVTPPMQNLVSQNQLDAPIFTIFFDKRDPDYYYPSNGLITYGGLDTKNCNANISY 239

  Fly   248 VPVSVPAYWQFKVNTIKT---NGTLLCNGCQAIADTGTSLIAVPLAAYRKINRQLGAT-DNDGEA 308
            ||||...||||||:..:.   |.|:  |..|||.|||:|...:|.:....|..|..|| |.....
 Worm   240 VPVSSKTYWQFKVDGFQVGTYNRTV--NRDQAIMDTGSSWFGLPYSVIAGIATQTNATWDLYASV 302

  Fly   309 F-VRCGRVSSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGLSFW---ILGDVFI 369
            : |.|..::|||.:...||...|.::..:|:..|..:..| |..|...::...|.   .||::||
 Worm   303 YTVPCSTMNSLPDLVFTIGAEKFPISAPEYVEDVGLDDGT-CALAMYGIDASGFGPSVTLGNIFI 366

  Fly   370 GKFYTVFDKGNERIGFA 386
            .::.:|||.||.|||||
 Worm   367 RRYCSVFDVGNARIGFA 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	117/338 (35%)
		Asp	75..388	CDD:278455	119/335 (36%)
asp-18	NP_507653.2	Asp	63..385	CDD:365818	119/333 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161985
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.860