Protein Alignment CG17134 and Ctsd

DIOPT Version :9

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_599161.2
• Gene: Ctsd / 171293
• RGDID: 621511
• Length: 407
• Species: Rattus norvegicus
• Alignment Length: 407
• Identity: 177/407 - (43%)
• Similarity: 248/407 - (60%)
• Gaps: 30/407 - (7%)

  Fly     6 VLLVLVG-IGHSAAKLNRVQLQ----VNKNFTKTHGSVKAEKTVLASKYSFLAETSFSVSSSGAT 65
            |||:::| :..|::.|.|:.|:    :.:..|:..|||  |..:|....     |.:|:.||..|
  Rat     6 VLLLILGLLAASSSALIRIPLRKFTSIRRTMTEVGGSV--EDLILKGPI-----TKYSMQSSPRT 63

  Fly    66 -----ENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSAS 125
                 |.|.|.::.:|||.|.||||.|.|.::|||||:||||||..|...:.||..|:||:|..|
  Rat    64 KEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKS 128

  Fly   126 STYVANGEEFAIEYGTGSLSGFLSNDIVTI------AGISIQNQTFGEALSEPGTTFVDAPFAGI 184
            ||||.||..|.|.||:|||||:||.|.|::      .||.::.|.||||..:||..|:.|.|.||
  Rat   129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGI 193

  Fly   185 LGLAFSAIAVDGVTPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVP 249
            ||:.:..|:|:.|.|.|||::.|.|:::.:.||||.|..|...||||:|||.||..|.|.|:|:.
  Rat   194 LGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLN 258

  Fly   250 VSVPAYWQFKVNTIKTNGTL-LC-NGCQAIADTGTSLIAVPLAAYRKINRQLGATD-NDGEAFVR 311
            |:..||||..::.::....| || .||:||.||||||:..|:...:::.:.:||.. ..||..:.
  Rat   259 VTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIP 323

  Fly   312 CGRVSSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYME----GLSFWILGDVFIGKF 372
            |.:|||||.:...:||..:.|.|..||:||:|.|:|.|:|.|..|:    ....|||||||||.:
  Rat   324 CEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCY 388

  Fly   373 YTVFDKGNERIGFARVA 389
            |||||:...|:|||:.|
  Rat   389 YTVFDREYNRVGFAKAA 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	153/328 (47%)
		Asp	75..388	CDD:278455	154/325 (47%)
Ctsd	NP_599161.2	A1_Propeptide	21..46	CDD:285240	8/26 (31%)
		Cathepsin_D2	73..403	CDD:133157	154/329 (47%)
		Asp	78..404	CDD:278455	154/325 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930