Protein Alignment CG17134 and Pgc

DIOPT Version :9

• Sequence 1: NP_609458.1
• Gene: CG17134 / 34494
• FlyBaseID: FBgn0032304
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_080249.2
• Gene: Pgc / 109820
• MGIID: 98909
• Length: 392
• Species: Mus musculus
• Alignment Length: 416
• Identity: 157/416 - (37%)
• Similarity: 227/416 - (54%)
• Gaps: 57/416 - (13%)

  Fly     1 MRQLLVLLVLVGIGHSAAKLNRVQLQ-------------VNKNFTKTHGSVKAEKTVLASKYSFL 52
            |:.::|.|:.:.:..:|  |.||.|:             |.|:|.|.|      |.....||.|.
Mouse     1 MKWMVVALLCLPLLEAA--LIRVPLKKMKSIRETMKEQGVLKDFLKNH------KYDPGQKYHFG 57

  Fly    53 AETSFSVSSSGATENLHNS---MNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTAC 114
            ....:||        |:..   |:..|||.|:||||.|.|.:||||||:||||.|..|  .:.||
Mouse    58 KFGDYSV--------LYEPMAYMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYC--QSEAC 112

  Fly   115 QRHNKYDSSASSTYVANGEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDA 179
            ..|.:|:.|.||||...|:.|:::||||||:||...|.:.:..|.:.||.||.:.:||||.||.|
Mouse   113 TTHTRYNPSKSSTYYTQGQTFSLQYGTGSLTGFFGYDTLRVQSIQVPNQEFGLSENEPGTNFVYA 177

  Fly   180 PFAGILGLAFSAIAVDGVTPPFDNMISQGLLDEPVISFYL-KRQGTAVRGGELILGGIDSSLYRG 243
            .|.||:|||:..::..|.|.....|:.:|.|.:|:...|| .:||:  .||:::.||:|.:||.|
Mouse   178 QFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGS--NGGQIVFGGVDENLYTG 240

  Fly   244 SLTYVPVSVPAYWQFKVNTI----KTNGTLLCNGCQAIADTGTSLIAVPLAAYRKINRQLGATDN 304
            .||::||:...|||..::..    :.:|....:|||.|.||||||:.:|.....::.:.:||.:.
Mouse   241 ELTWIPVTQELYWQITIDDFLIGNQASGWCSSSGCQGIVDTGTSLLVMPAQYLNELLQTIGAQEG 305

  Fly   305 D-GEAFVRCGRVSSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGLS-------- 360
            : |:.||.|..|||||.:...:.|..|.|:|..||::  :.|.  ||..   :|.||
Mouse   306 EYGQYFVSCDSVSSLPTLTFVLNGVQFPLSPSSYIIQ--EEGS--CMVG---LESLSLNAESGQP 363

  Fly   361 FWILGDVFIGKFYTVFDKGNERIGFA 386
            .|||||||:..:|.|||.||.|:|.|
Mouse   364 LWILGDVFLRSYYAVFDMGNNRVGLA 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17134	NP_609458.1	pepsin_retropepsin_like	70..386	CDD:299705	136/332 (41%)
		Asp	75..388	CDD:278455	136/326 (42%)
Pgc	NP_080249.2	A1_Propeptide	18..46	CDD:285240	8/27 (30%)
		pepsin_retropepsin_like	73..391	CDD:299705	136/328 (41%)
		Asp	75..390	CDD:278455	136/326 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841598
Domainoid	1	1.000	297	1.000	Domainoid score	I1457
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2599
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.810