Protein Alignment CG6508 and YPS6

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_012305.3
• Gene: YPS6 / 854857
• SGDID: S000001478
• Length: 537
• Species: Saccharomyces cerevisiae
• Alignment Length: 458
• Identity: 106/458 - (23%)
• Similarity: 185/458 - (40%)
• Gaps: 113/458 - (24%)

  Fly    55 VDRQSSQTTQVLANGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWV------------------- 100
            |.:::......:.||..: |.:::.||||||...||.||||||:.|
Yeast    49 VFKRNEVLNTTVINGIGV-YVVKMEIGTPPQTLYLQLDTGSSDMIVNNADIAYCKSMSDGSDYAS 112

  Fly   101 -------------PSVKCSST--NEACQKHNKYNSSASSSHVEDGKGFSIQYGSGS-LSGFLSTD 149
                         ||...||.  |..|.....:::|.||:...:...|:..||.|: .:|...||
Yeast   113 TDNYELTATFNGLPSTTISSEAYNTLCSYWGTFDASNSSTFENNATFFNNTYGDGTYYAGTYGTD 177

  Fly   150 TVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMA--FASISGGV-------TTPF--DN--- 200
            .|..:.:.:.:.||..:.|..|:.      .||:|::  .|..:.|:       .|||  ||
Yeast   178 VVSFENITLNDFTFGVSNDTIGNP------SGILGISLPIAEFTDGIEYALALNRTPFIYDNFPM 236

  Fly   201 -IIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPV--------SMPAYWQFT 256
             :..||.:....:|::|  :|.....|.:::|.:|:|.|.|.:..:|:        |.|. ...|
Yeast   237 ELKNQGKINKIAYSLFL--NGPDAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPG-MIIT 298

  Fly   257 ANSVKI----EGILLCNGCQ--AIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFV-DCSSLC 314
            |.||.|    .|....:..|  .:.|:||:...:|....:||.|..:...:.|.:.:: |||.:
Yeast   299 AQSVAILDSESGNKTVSDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCSKV- 362

  Fly   315 RLPN---VNLNIGGTTYTLTPKDYIYKVQADNNQTLCLSGFTYLQGNLLWILGDIFLGKVYTVFD 376
               |   ::::.||...:....:::     .:.:..|:  ....|....::|||.||...|.|:|
Yeast   363 ---NDTLLSVDFGGFNISANISNFV-----TSAKDRCV--LNVKQSESTYMLGDAFLVDAYVVYD 417

  Fly   377 VGKERIGFAKL---KKHSSYRV-------------YASSYVKEPSS-------YGIDYPFYGDEY 418
            :....|..|:.   .:.....|             |.|::|.:|.|       ..:.:..| .|:
Yeast   418 LENYEISIAQASFNNQEEDIEVISDTVPGATPAPGYFSTWVYKPGSPIGTGDFINVSWTSY-SEF 481

  Fly   419 SRF 421
            |::
Yeast   482 SQY 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	95/385 (25%)
		Asp	73..387	CDD:278455	94/381 (25%)
YPS6	NP_012305.3	SAP_like	65..428	CDD:133141	94/383 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770