Protein Alignment CG6508 and Pga5

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_067428.2
• Gene: Pga5 / 58803
• MGIID: 1915935
• Length: 387
• Species: Mus musculus
• Alignment Length: 392
• Identity: 141/392 - (35%)
• Similarity: 215/392 - (54%)
• Gaps: 35/392 - (8%)

  Fly     6 LIIIPLFLLLLDHSMGQ-LRRTPITRQINQN--KTHANVKAEKILLAAKYFLVDRQSSQTTQVLA 67
            |:.|||..:   .||.: ||.:.:.:...:.  ::.|:|..|:          .|..:.|.:.:.
Mouse    16 LVKIPLMKI---KSMRENLRESQVLKDYLEKYPRSRAHVLLEQ----------RRNPAVTYEPMR 67

  Fly    68 NGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSHVEDGKG 132
            |..:|.|...:.||||||.|.:..|||||.|||||:.|||  .||..|..:|...||:.:..|:.
Mouse    68 NYLDLVYIGIISIGTPPQEFRVVLDTGSSVLWVPSIYCSS--PACAHHKAFNPLRSSTFLVSGRP 130

  Fly   133 FSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFASIS-GGVTT 196
            .::.||||.:||||:.|||.|..:.:..|.|..:::|||......:||||:|:.:.::. .|:|.
Mouse   131 VNVAYGSGEMSGFLAYDTVRIGDLTVVAQAFGLSLEEPGIFMEYAVFDGILGLGYPNLGLQGITP 195

  Fly   197 PFDNIIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPVSMPAYWQFTANSVK 261
            .|||:..|||:...:|:.||  ....:.|..::.||:|.|.|.|.:::||||.|:|||...:|:.
Mouse   196 VFDNLWLQGLIPQNLFAFYL--SSKDEKGSMLMLGGVDPSYYHGELHWVPVSKPSYWQLAVDSIS 258

  Fly   262 IEG-ILLCN-GCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVDCSSLCRLPNVNLNIG 324
            :.| ::.|: |||.|.||||||:..|..:...|..::.|..:||||.|:.|.::..||::...||
Mouse   259 MNGEVIACDGGCQGIMDTGTSLLTGPRSSIVNIQNLIGAKASGDGEYFLKCDTINTLPDIVFTIG 323

  Fly   325 GTTYTLTPKDYIYKVQADNNQTLCLSGFTYLQG------NLLWILGDIFLGKVYTVFDVGKERIG 383
            ..||.:....||.|.::.|    |.|.|.  :|      ..:|:|||:||...:||||....|||
Mouse   324 SVTYPVPASAYIRKDRSHN----CRSNFE--EGMDDPSDPEMWVLGDVFLRLYFTVFDRANNRIG 382

  Fly   384 FA 385
            .|
Mouse   383 LA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	128/327 (39%)
		Asp	73..387	CDD:278455	126/322 (39%)
Pga5	NP_067428.2	A1_Propeptide	16..44	CDD:285240	8/30 (27%)
		pepsin_retropepsin_like	64..385	CDD:299705	128/331 (39%)
		Asp	74..386	CDD:278455	126/321 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860