Protein Alignment CG6508 and Pga5

DIOPT Version :10

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_067428.2
• Gene: Pga5 / 58803
• MGIID: 1915935
• Length: 387
• Species: Mus musculus
• Alignment Length: 392
• Identity: 141/392 - (35%)
• Similarity: 215/392 - (54%)
• Gaps: 35/392 - (8%)

  Fly     6 LIIIPLFLLLLDHSMGQ-LRRTPITRQINQN--KTHANVKAEKILLAAKYFLVDRQSSQTTQVLA 67
            |:.|||..:   .||.: ||.:.:.:...:.  ::.|:|..|:          .|..:.|.:.:.
Mouse    16 LVKIPLMKI---KSMRENLRESQVLKDYLEKYPRSRAHVLLEQ----------RRNPAVTYEPMR 67

  Fly    68 NGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSHVEDGKG 132
            |..:|.|...:.||||||.|.:..|||||.|||||:.|||  .||..|..:|...||:.:..|:.
Mouse    68 NYLDLVYIGIISIGTPPQEFRVVLDTGSSVLWVPSIYCSS--PACAHHKAFNPLRSSTFLVSGRP 130

  Fly   133 FSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFASIS-GGVTT 196
            .::.||||.:||||:.|||.|..:.:..|.|..:::|||......:||||:|:.:.::. .|:|.
Mouse   131 VNVAYGSGEMSGFLAYDTVRIGDLTVVAQAFGLSLEEPGIFMEYAVFDGILGLGYPNLGLQGITP 195

  Fly   197 PFDNIIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPVSMPAYWQFTANSVK 261
            .|||:..|||:...:|:.||  ....:.|..::.||:|.|.|.|.:::||||.|:|||...:|:.
Mouse   196 VFDNLWLQGLIPQNLFAFYL--SSKDEKGSMLMLGGVDPSYYHGELHWVPVSKPSYWQLAVDSIS 258

  Fly   262 IEG-ILLCN-GCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVDCSSLCRLPNVNLNIG 324
            :.| ::.|: |||.|.||||||:..|..:...|..::.|..:||||.|:.|.::..||::...||
Mouse   259 MNGEVIACDGGCQGIMDTGTSLLTGPRSSIVNIQNLIGAKASGDGEYFLKCDTINTLPDIVFTIG 323

  Fly   325 GTTYTLTPKDYIYKVQADNNQTLCLSGFTYLQG------NLLWILGDIFLGKVYTVFDVGKERIG 383
            ..||.:....||.|.::.|    |.|.|.  :|      ..:|:|||:||...:||||....|||
Mouse   324 SVTYPVPASAYIRKDRSHN----CRSNFE--EGMDDPSDPEMWVLGDVFLRLYFTVFDRANNRIG 382

  Fly   384 FA 385
            .|
Mouse   383 LA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:472175	128/327 (39%)
Pga5	NP_067428.2	A1_Propeptide	18..44	CDD:462326	7/28 (25%)
		pepsin_retropepsin_like	64..385	CDD:472175	128/331 (39%)