Protein Alignment CG6508 and Bace2

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_062390.3
• Gene: Bace2 / 56175
• MGIID: 1860440
• Length: 514
• Species: Mus musculus
• Alignment Length: 375
• Identity: 103/375 - (27%)
• Similarity: 173/375 - (46%)
• Gaps: 70/375 - (18%)

  Fly    62 TTQVLANGFNLE------YTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNS 120
            |...||...||:      |.:.:.||||||...:..|||||:..|.....|..:      ..::|
Mouse    70 TANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHSYID------TYFDS 128

  Fly   121 SASSSHVEDGKGFSIQYGSGSLSGFLSTDTVDI-DGMVIRNQTF---AEAIDEPGSAFVNTI-FD 180
            .:||::...|...:::|..||.:||:..|.|.| .|.   |.:|   ...|.|..:.|:..| ::
Mouse   129 ESSSTYHSKGFDVTVKYTQGSWTGFVGEDLVTIPKGF---NSSFLVNIATIFESENFFLPGIKWN 190

  Fly   181 GIIGMAFASI---SGGVTTPFDNIIRQGLVKHPVFSVY-----LRRDGTSQSGGEVIWGGIDRSI 237
            ||:|:|:|::   |..:.|.||:::.|..:. .:||:.     |...|:..:||.::.|||:.|:
Mouse   191 GILGLAYAALAKPSSSLETFFDSLVAQAKIP-DIFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSL 254

  Fly   238 YRGCINYVPVSMPAYWQFTANSVKIEGILL---C---NGCQAIADTGTSLIAVPLRAYKAINKVL 296
            |:|.|.|.|:....|:|.....::|.|..|   |   |..:||.|:||:|:.:|.:.:.|:.:.:
Mouse   255 YKGDIWYTPIKEEWYYQIEILKLEIGGQNLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAV 319

  Fly   297 NAT----DAGDG---EAFVDC-----SSLCRLPNVNLNIGGTT------YTLTPKDYIYKVQADN 343
            ..|    :..||   .|.:.|     :.....|.:::.:....      .|:.|:.||
Mouse   320 ARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRDENASRSFRITILPQLYI------- 377

  Fly   344 NQTLCLSGFTY--------LQGNLLWILGDIFLGKVYTVFDVGKERIGFA 385
             |.:..:||.|        ...|.| ::|...:...|.|||..:.|:|||
Mouse   378 -QPMMGAGFNYECYRFGISSSTNAL-VIGATVMEGFYVVFDRAQRRVGFA 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	100/369 (27%)
		Asp	73..387	CDD:278455	98/364 (27%)
Bace2	NP_062390.3	beta_secretase_like	85..446	CDD:133140	98/360 (27%)
		Asp	88..425	CDD:278455	96/355 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740