DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6508 and pga4

DIOPT Version :9

Sequence 1:	NP_609457.1	Gene:	CG6508 / 34493	FlyBaseID:	FBgn0032303	Length:	423	Species:	Drosophila melanogaster
Sequence 2:	XP_002942158.1	Gene:	pga4 / 496914	XenbaseID:	XB-GENE-979768	Length:	384	Species:	Xenopus tropicalis

Alignment Length:	336	Identity:	143/336 - (42%)
Similarity:	201/336 - (59%)	Gaps:	20/336 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 AAKYFLVDRQSSQTTQVLANGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQ 113
            |:|||....|||  .:||.|..::||...:.||||||.|.:.|||||::||||||.|||:  ||.
Frog    49 ASKYFPTLAQSS--AEVLQNYMDIEYYGTISIGTPPQEFTVIFDTGSANLWVPSVYCSSS--ACT 109

  Fly   114 KHNKYNSSASSSHVEDGKGFSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTI 178
            .||::|...|::........|||||:||:||||..||:.:..:.|.||.|..:..||||....:.
Frog   110 NHNRFNPQQSTTFQATNTPVSIQYGTGSMSGFLGYDTLQVGNIKISNQMFGLSESEPGSFLYYSP 174

  Fly   179 FDGIIGMAFASISGGVTTP-FDNIIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCI 242
            ||||:|:||.||:....|| |||:..|||:...:|||||..||  |||..|::||:|.|.|.|.:
Frog   175 FDGILGLAFPSIASSQATPVFDNMWSQGLIPQNLFSVYLSSDG--QSGSYVLFGGVDTSYYSGSL 237

  Fly   243 NYVPVSMPAYWQFTANSVKIEG-ILLCN-GCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGE 305
            |:||::...|||...:|:.|.| ::.|: .||||.||||||:..|......|...:.|:...:|:
Frog   238 NWVPLTAETYWQIILDSISINGQVIACSQSCQAIVDTGTSLMTGPTTPIANIQYYIGASQDSNGQ 302

  Fly   306 AFVDCSSLCRLPNVNLNIGGTTYTLTPKDYIYKVQADNNQTLCLSGFTYL-----QGNLLWILGD 365
            ..::|:::..:|.:...|.|..|.|.|..|:.:     ||..|.|||..:     .|: ||||||
Frog   303 YVINCNNISNMPTIVFTINGVQYPLPPTAYVRQ-----NQQGCSSGFQAMTLPTNSGD-LWILGD 361

  Fly   366 IFLGKVYTVFD 376
            :|:.:.:.|||
Frog   362 VFIRQYFVVFD 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	134/317 (42%)
CG6508	NP_609457.1	Asp	73..387	CDD:278455	133/312 (43%)
pga4	XP_002942158.1	A1_Propeptide	16..44	CDD:369623
pga4	XP_002942158.1	pepsin_A	62..382	CDD:133145	136/321 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.110