Protein Alignment CG6508 and cathD

DIOPT Version :10

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Alignment Length: 398
• Identity: 177/398 - (44%)
• Similarity: 238/398 - (59%)
• Gaps: 16/398 - (4%)

  Fly     1 MEVGQLIIIPLFLLLLDHSMGQ----LRRTPITRQINQNKTHANVKAEKILLAAKYFLVDRQSSQ 61
            |:...|:::......:.|...|    |.|.|:.:..:..:..|:|..|...|..:|     ....
  Fly     1 MQKVALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTELQQLRIRY-----GGGD 60

  Fly    62 TTQVLANGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSH 126
            ..:.|:|..:.:|...:.||:|||.|.:.||||||:|||||.||..||.||..||||::|.|.::
  Fly    61 VPEPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTY 125

  Fly   127 VEDGKGFSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFASIS 191
            .::|..|:||||||||||:||||||.|.|:.|::||||||:.|||..||...||||:|:.:.|||
  Fly   126 TKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSIS 190

  Fly   192 -GGVTTPFDNIIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPVSMPAYWQF 255
             ..|..||..:..|||:..||||.||.||..|..|||:|:||.|.:.|.|...|:||:..||||.
  Fly   191 VDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQI 255

  Fly   256 TANSVKIEGILLC-NGCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVDCSSLCRLPNV 319
            ..::..|..:.|| .|||.||||||||||.||....:||:.:..|....|:..|.|..:.:||.:
  Fly   256 KMDAASIGDLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVI 320

  Fly   320 NLNIGGTTYTLTPKDYIYKVQADNNQTLCLSGFTYLQ----GNLLWILGDIFLGKVYTVFDVGKE 380
            ...:||.|:.|..||||.:| |...:|:|||||..|.    ...||||||:|:||.||.||:|.:
  Fly   321 KFVLGGKTFELEGKDYILRV-AQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGND 384

  Fly   381 RIGFAKLK 388
            |:|||..|
  Fly   385 RVGFADAK 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:472175	162/323 (50%)
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	6/26 (23%)
		pepsin_retropepsin_like	62..389	CDD:472175	162/327 (50%)