Protein Alignment CG6508 and bace2

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: XP_009289748.1
• Gene: bace2 / 449818
• ZFINID: ZDB-GENE-041010-68
• Length: 503
• Species: Danio rerio
• Alignment Length: 420
• Identity: 106/420 - (25%)
• Similarity: 179/420 - (42%)
• Gaps: 86/420 - (20%)

  Fly    36 KTHANVKAEKILLAAKY---FLVDRQSSQTTQVLA-NGFNLE----------------------- 73
            |:|:..|....:.|.|:   ..:|.:..|..:..| :|.:|.
Zfish    15 KSHSVFKIPLNIFAGKFNASVQLDLRPLQKNEAAAKSGLSLASDPAGIVNFLDMINNLKGDSGRG 79

  Fly    74 YTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKH----NKYNSSASSSHVEDGKGFS 134
            |.:::.||||.|..|:..|||||:..|          |...|    :.:|.:.||::....:..:
Zfish    80 YYMQMIIGTPGQTLNILVDTGSSNFAV----------AAAAHPYITHYFNRALSSTYQSTERAVA 134

  Fly   135 IQYGSGSLSGFLSTDTVDI----DGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAF---ASISG 192
            ::|..|...|.|.||.:.|    .|.:..|  .|..:...|.......:.||:|:|:   |....
Zfish   135 VKYTQGEWEGELGTDLITIPEGPSGAITIN--IAAILTSEGFFLPGINWQGILGLAYPLLARPDP 197

  Fly   193 GVTTPFDNIIRQGLVKHPVFSVYLRRDGTSQS------GGEVIWGGIDRSIYRGCINYVPVSMPA 251
            .|...|::::||..:. .|||:.:...|...|      ||.:|.||::.:::||.|.|.||....
Zfish   198 SVEPFFNSVVRQTGIP-DVFSLQMCGAGVPASTTGDPAGGSLIMGGVEPTLHRGPIWYTPVLEEW 261

  Fly   252 YWQFTANSVKI--EGILL-C---NGCQAIADTGTSLIAVPLRAYKAINKVLNATDAGD--GEAFV 308
            |:|.....:::  :.:.| |   |..:||.|:||:|:.:|...:.|:...:..|...|  ...|.
Zfish   262 YYQVEVLKLEVGDQNLNLDCKEYNSDKAIVDSGTTLLRLPANVFTAVVDTIMQTSLIDDFSAGFF 326

  Fly   309 DCSSL-CRL---------PNVNLNIGGTT------YTLTPKDYIYKVQADNNQTL-CLS-GFTYL 355
            |.:.| |.:         |.|::.:.||.      .|:.|:.||..| .|.:.|| |.. |.:..
Zfish   327 DGTKLACWMRGESPWRFFPKVSIYLRGTNTSQSFRITILPQLYIQPV-TDIDGTLDCFRFGISPS 390

  Fly   356 QGNLLWILGDIFLGKVYTVFDVGKERIGFA 385
            ...|  ::|...:...|.:||..::|:|||
Zfish   391 ANGL--VIGATVMEGFYVIFDRAQKRVGFA 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	98/384 (26%)
		Asp	73..387	CDD:278455	96/379 (25%)
bace2	XP_009289748.1	beta_secretase_like	77..439	CDD:133140	96/358 (27%)
		Asp	80..418	CDD:278455	94/353 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585940
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740