Protein Alignment CG6508 and Bace

DIOPT Version :10

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 378
• Identity: 192/378 - (50%)
• Similarity: 256/378 - (67%)
• Gaps: 14/378 - (3%)

  Fly     9 IPLFLLLLDHSMGQLRRTPITRQINQNKTHANVKAEKILLAAKYFLVDRQSSQTTQVLANGFNLE 73
            |.:.:||...:..:|.|.||.::.|..||..||.|||..|..||.|...:|....| |:|..|:.
  Fly     5 IAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDEEQ-LSNSMNMA 68

  Fly    74 YTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSHVEDGKGFSIQYG 138
            |...:.||||.|.|.:.||:|||:|||||..|.|  :||..||:|:|||||::|.:|:.||||||
  Fly    69 YYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKS--DACLTHNQYDSSASSTYVANGESFSIQYG 131

  Fly   139 SGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFASIS-GGVTTPFDNII 202
            :|||:|:|||||||::|:.|::|||||:.:|||:.|.:..||||:|||:.|:: .||..||.|::
  Fly   132 TGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMV 196

  Fly   203 RQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPVSMPAYWQFTANSVKIEGILL 267
            .||||.:.|||.||.|||||..|||:|:||.|.|:|.|.:.|||:|...|||||.....|:|..|
  Fly   197 SQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGYSL 261

  Fly   268 CNGCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVDCSSLCRLPNVNLNIGGTTYTLTP 332
            |:.||||||||||||..|..||..::::||..:.|    ::||||:..||:|..|||||.:.|.|
  Fly   262 CDDCQAIADTGTSLIVAPYNAYITLSEILNVGEDG----YLDCSSVSSLPDVTFNIGGTNFVLKP 322

  Fly   333 KDYIYKVQADNNQTLCLSGFTYLQGNLLWILGDIFLGKVYTVFDVGKERIGFA 385
            ..||  :|:|.|   |:|.|.|: |...|||||:|:|:.||.||:|..|||||
  Fly   323 SAYI--IQSDGN---CMSAFEYM-GTDFWILGDVFIGQYYTEFDLGNNRIGFA 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:472175	170/319 (53%)
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	170/322 (53%)