Protein Alignment CG6508 and Pgc

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_579818.1
• Gene: Pgc / 24864
• RGDID: 3943
• Length: 392
• Species: Rattus norvegicus
• Alignment Length: 406
• Identity: 147/406 - (36%)
• Similarity: 224/406 - (55%)
• Gaps: 46/406 - (11%)

  Fly     6 LIIIPLFLLLLDHSMGQLRRTPITRQINQNKTHANVKAEKILLAAKYFLVDRQSSQTTQVLANGF 70
            :::..|.|.||:.|   |.|.|:.:..:..:|   :|.:.:|   |.||...:.....:.....|
  Rat     4 MVVALLCLPLLEAS---LLRVPLRKMKSIRET---MKEQGVL---KDFLKTHKYDPGQKYHFGNF 59

  Fly    71 NLEYTI--------------RLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSS 121
            . :|::              .:.||||||.|.:.||||||:|||.||.|.|  |||..|.::|.|
  Rat    60 G-DYSVLYEPMAYMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQS--EACTTHARFNPS 121

  Fly   122 ASSSHVEDGKGFSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMA 186
            .||::..:|:.||:|||:|||:||...||:.:..:.:.||.|..:.:|||:.||...||||:|:|
  Rat   122 KSSTYYTEGQTFSLQYGTGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLA 186

  Fly   187 FASI-SGGVTTPFDNIIRQGLVKHPVFSVYLRRDGTSQ--SGGEVIWGGIDRSIYRGCINYVPVS 248
            :..: |||.||....::.:|.:..|:|.|||   |:.|  :||::::||:|:::|.|.|.:|||:
  Rat   187 YPGLSSGGATTALQGMLGEGALSQPLFGVYL---GSQQGSNGGQIVFGGVDKNLYTGEITWVPVT 248

  Fly   249 MPAYWQFTANSVKI----EGILLCNGCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVD 309
            ...|||.|.:...|    .|.....|||.|.||||||:.:|.:....:.:.:.|.:...||.||.
  Rat   249 QELYWQITIDDFLIGDQASGWCSSQGCQGIVDTGTSLLVMPAQYLSELLQTIGAQEGEYGEYFVS 313

  Fly   310 CSSLCRLPNVNLNIGGTTYTLTPKDYIYKVQADNNQTLCLSG-----FTYLQGNLLWILGDIFLG 369
            |.|:..||.::..:.|..:.|:|..||  :|.||   .|:.|     .|...|..||||||:||.
  Rat   314 CDSVSSLPTLSFVLNGVQFPLSPSSYI--IQEDN---FCMVGLESISLTSESGQPLWILGDVFLR 373

  Fly   370 KVYTVFDVGKERIGFA 385
            ..|.:||:|..::|.|
  Rat   374 SYYAIFDMGNNKVGLA 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	133/344 (39%)
		Asp	73..387	CDD:278455	132/339 (39%)
Pgc	NP_579818.1	A1_Propeptide	18..46	CDD:400357	9/33 (27%)
		pepsin_retropepsin_like	73..391	CDD:416259	131/327 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.760