Protein Alignment CG6508 and Ren1

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_112469.1
• Gene: Ren1 / 19701
• MGIID: 97898
• Length: 402
• Species: Mus musculus
• Alignment Length: 373
• Identity: 150/373 - (40%)
• Similarity: 210/373 - (56%)
• Gaps: 17/373 - (4%)

  Fly    23 LRRTPITRQINQNKTHANVKAEKILLAAKYFLVDRQSSQTT----QVLANGFNLEYTIRLCIGTP 83
            |::.|..|:|.:.:     ..:...|:|::.:..::.|.|.    .||.|..|.:|...:.||||
Mouse    34 LKKMPSVREILEER-----GVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTP 93

  Fly    84 PQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSHVEDGKGFSIQYGSGSLSGFLST 148
            ||.|.:.|||||::|||||.|||....||..|:.|.||.|||::|:|..|:|.||||.:.||||.
Mouse    94 PQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQ 158

  Fly   149 DTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAF-ASISGGVTTPFDNIIRQGLVKHPVF 212
            |:|.:.|:.: .|||.|..:.|...|:...|||::||.| |...||||..||:|:.||::|..||
Mouse   159 DSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVF 222

  Fly   213 SVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPVSMPAYWQFTANSVKI-EGILLC-NGCQAIA 275
            |||..| |:...||||:.||.|...|:|..:||.:|....||.|...|.: ...||| .||..:.
Mouse   223 SVYYNR-GSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVV 286

  Fly   276 DTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVDCSSLCRLPNVNLNIGGTTYTLTPKDYI--YK 338
            |||:|.|:.|..:.|.|.:.|.|.:....|..|:||.:..||:::.::||..|||:..||:  |.
Mouse   287 DTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYP 351

  Fly   339 VQADNNQTLCLSGFTY-LQGNLLWILGDIFLGKVYTVFDVGKERIGFA 385
            .:.|...||.|..... .....:|:||..|:.|.||.||....|||||
Mouse   352 NRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	140/324 (43%)
		Asp	73..387	CDD:278455	138/319 (43%)
Ren1	NP_112469.1	A1_Propeptide	29..54	CDD:285240	4/24 (17%)
		renin_like	76..401	CDD:133154	141/326 (43%)
		Asp	83..401	CDD:278455	138/319 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.810