Protein Alignment CG6508 and asp-12

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_505134.1
• Gene: asp-12 / 179210
• WormBaseID: WBGene00017678
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 337
• Identity: 115/337 - (34%)
• Similarity: 182/337 - (54%)
• Gaps: 20/337 - (5%)

  Fly    68 NGF-NLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSHVEDGK 131
            |.| ::||...:.||||||.|.:..||||::||||...|..|   |:..::::||.|::..::|:
 Worm    66 NDFGDVEYLGNITIGTPPQQFIVVLDTGSANLWVPGSNCDGT---CKGKSEFDSSKSTTFKKNGQ 127

  Fly   132 GFSIQYGSGSLSGFLSTDTVDIDG-----MVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFASIS 191
            .:.|||.|||..|.:..|||...|     :::.:.||..| ....|.|.|...:||:|:||.|::
 Worm   128 SWQIQYESGSAKGIMGVDTVAFGGASEQQLLVPSTTFGIA-SHISSNFKNDAAEGILGLAFTSLA 191

  Fly   192 -GGVTTPFDNIIRQGLVKHPVFSVYLRRDGTSQS--GGEVIWGGIDRSIYRGCINYVPVSMPAYW 253
             .|||.|..|.|.:.::..|:|:|:|...||:::  ||...:|.:|.:.....|.|.|:|...|:
 Worm   192 VDGVTPPLINAINKKILDQPLFTVFLEHKGTAKNVGGGVFTYGAVDTTNCGPVIAYQPLSSATYY 256

  Fly   254 QFTANSVKIEGILLCNGCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEA-FVDCSSLCRLP 317
            ||.|:..|:.........|.|:|||:|||..|........:.|.|....|.:| ::.||:  ...
 Worm   257 QFVADGFKLGSYSNNKKSQVISDTGSSLIGGPSAVINGFAQALGAKYHSDDDAYYLPCST--SKG 319

  Fly   318 NVNLNIGGTTYTLTPKDYIYKVQADNNQTLCLSGFTYLQGNL--LWILGDIFLGKVYTVFDVGKE 380
            .:::.|||..|::.|.:||..|  ....|...:.|::..|..  .||.||.|:.:...::|:|::
 Worm   320 TLDITIGGNVYSIEPVNYILDV--GMGDTCVFAAFSFDFGGFGPSWIFGDPFIRQYCNIYDIGQQ 382

  Fly   381 RIGFAKLKKHSS 392
            ||||||..:.||
 Worm   383 RIGFAKSLQPSS 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	111/329 (34%)
		Asp	73..387	CDD:278455	110/324 (34%)
asp-12	NP_505134.1	Asp	72..388	CDD:365818	109/323 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850