Protein Alignment CG6508 and Napsa

DIOPT Version :9

• Sequence 1: NP_609457.1
• Gene: CG6508 / 34493
• FlyBaseID: FBgn0032303
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_032463.1
• Gene: Napsa / 16541
• MGIID: 109365
• Length: 419
• Species: Mus musculus
• Alignment Length: 412
• Identity: 164/412 - (39%)
• Similarity: 227/412 - (55%)
• Gaps: 38/412 - (9%)

  Fly    10 PLFLLLLDHSMGQLR-------RTPITRQINQNKTHANVKAEKILLAAKYFLVDRQSSQTTQ--- 64
            ||.||||...:|.|.       |.|:.|      .|.   ..:||.....:....:.|:|:.
Mouse     3 PLLLLLLCLLLGNLEPEEAKLIRVPLQR------IHL---GHRILNPLNGWEQLAELSRTSTSGG 58

  Fly    65 -----VLANGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASS 124
                 .|:...|.:|...:.:|||||.|.:.||||||:|||||.:|...:.||..|:::|..|||
Mouse    59 NPSFVPLSKFMNTQYFGTIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFNPKASS 123

  Fly   125 SHVEDGKGFSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFAS 189
            |...:|..|:||||:|.|||.||.|.:.|.|:.....||.||:.||...|....||||:|:.|.:
Mouse   124 SFRPNGTKFAIQYGTGRLSGILSQDNLTIGGIHDAFVTFGEALWEPSLIFALAHFDGILGLGFPT 188

  Fly   190 IS-GGVTTPFDNIIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPVSMPAYW 253
            :: |||..|.|.::.|||::.||||.||.||.....|||::.||.|.:.|...:.::||::||||
Mouse   189 LAVGGVQPPLDAMVEQGLLEKPVFSFYLNRDSEGSDGGELVLGGSDPAHYVPPLTFIPVTIPAYW 253

  Fly   254 QFTANSVKI-EGILLC-NGCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVDCSSLCRL 316
            |....|||: .|:.|| .||.||.|||||||..|....:|:||.:......:|:.|:.||....|
Mouse   254 QVHMESVKVGTGLSLCAQGCSAILDTGTSLITGPSEEIRALNKAIGGYPFLNGQYFIQCSKTPTL 318

  Fly   317 PNVNLNIGGTTYTLTPKDYIYKV-QADNNQTLCLSGFTYLQ----GNLLWILGDIFLGKVYTVFD 376
            |.|:.::||..:.||.:||:.|: |:|..  |||.||..|.    ...||||||:|||....|||
Mouse   319 PPVSFHLGGVWFNLTGQDYVIKILQSDVG--LCLLGFQALDIPKPAGPLWILGDVFLGPYVAVFD 381

  Fly   377 VGKE----RIGFAKLKKHSSYR 394
            .|.:    |:|.|:.:..|:.|
Mouse   382 RGDKNVGPRVGLARAQSRSTDR 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	144/329 (44%)
		Asp	73..387	CDD:278455	144/325 (44%)
Napsa	NP_032463.1	pepsin_retropepsin_like	68..394	CDD:299705	144/327 (44%)
		Asp	72..396	CDD:278455	144/325 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..419		4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841596
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.820