DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6508 and LOC100493461

DIOPT Version :9

Sequence 1:	NP_609457.1	Gene:	CG6508 / 34493	FlyBaseID:	FBgn0032303	Length:	423	Species:	Drosophila melanogaster
Sequence 2:	XP_002938556.2	Gene:	LOC100493461 / 100493461	-ID:	-	Length:	402	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	145/332 - (43%)
Similarity:	203/332 - (61%)	Gaps:	10/332 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 TTQVLANGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSH 126
            ||:.|.:..|.:|...:.:|||||.|::.||||||:.||||..|.|  ||||.|.::.|..|:|:
Frog    69 TTEYLVDYMNAQYYGEISVGTPPQNFSVVFDTGSSNFWVPSSYCLS--EACQVHERFKSFESTSY 131

  Fly   127 VEDGKGFSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFASIS 191
            ...|:.|||.||:|.|.|....||:.|..|.|..|.|.|:|.|||..||...|||::|:.:.|::
Frog   132 EHGGRPFSIHYGTGQLVGVTGRDTLRISNMSIEGQDFGESILEPGRTFVLAQFDGVLGLGYPSLA 196

  Fly   192 -GGVTTPFDNIIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINYVPVSMPAYWQF 255
             .|....||.|:.|.||:..:||.:|.||..|:.|||:|:||||.|:|:|.|:::|::...|||.
Frog   197 VAGAVPVFDRIVNQKLVEQQLFSFHLNRDYDSEYGGELIFGGIDHSLYKGQIHWIPLTEKGYWQI 261

  Fly   256 TANSVKIEG-ILLC-NGCQAIADTGTSLIAVPLRAYKAINKVLNATDAGDGEAFVDCSSLCRLPN 318
            ..::||::| .:.| :.||.|.|:|||||..|....|.:.::|.||....||..:|||.:..||.
Frog   262 RLDNVKVDGEAMFCQSSCQVIVDSGTSLITGPKAEIKKLQELLGATPTLFGEYILDCSRVSSLPR 326

  Fly   319 VNLNIGGTTYTLTPKDYIYKVQADNNQTLCLSGFTYL----QGNLLWILGDIFLGKVYTVFDVGK 379
            |...||...|||||:.|..|.::..:. .||:||..:    :...||||||||:.|.|:|||...
Frog   327 VTFTIGQRDYTLTPEQYTIKERSQKSD-FCLTGFQAMDISTKDGPLWILGDIFMSKFYSVFDREH 390

  Fly   380 ERIGFAK 386
            :|||.||
Frog   391 DRIGLAK 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6508	NP_609457.1	pepsin_retropepsin_like	68..386	CDD:299705	140/324 (43%)
CG6508	NP_609457.1	Asp	73..387	CDD:278455	141/321 (44%)
LOC100493461	XP_002938556.2	A1_Propeptide	17..45	CDD:400357
LOC100493461	XP_002938556.2	pepsin_retropepsin_like	75..397	CDD:416259	140/324 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010