DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6724 and AT5G15550

DIOPT Version :9

Sequence 1:	NP_609452.1	Gene:	CG6724 / 34488	FlyBaseID:	FBgn0032298	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_001332618.1	Gene:	AT5G15550 / 831408	AraportID:	AT5G15550	Length:	433	Species:	Arabidopsis thaliana

Alignment Length:	430	Identity:	132/430 - (30%)
Similarity:	216/430 - (50%)	Gaps:	28/430 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDVDNGEGQVQVHLK--TKQEH-YAVPDVPYAIDGTVTTVELNTFVNALLRQKDGSSDTD-FDFL 61
            ||:|..:...::|:|  ||.:. :.||....||...||.:.|::.||:::..::....|: ||||
plant     1 MDIDGEDVSRRLHVKFVTKLDSPFKVPVNSVAIPSNVTRLGLSSIVNSIIESENPEWKTEPFDFL 65

  Fly    62 VFDEYLRGRLCDHLREKAISFEDAIEIEYVERFPAPEPQDCLLHDDWVSAVKARG-KWILSGCYD 125
            :..|.:|..|.:.|..|.||.|..:||||:......:.::..|||||||||.... ::||:||||
plant    66 IDGELIRMSLEEFLLAKGISAERTLEIEYIRAVTPRKEEEPSLHDDWVSAVNGSSPRFILTGCYD 130

  Fly   126 NTLNLWTNKG--KHILTISGHTAPIKAVDWI-SLDEETGRFVSTSQDQTAMLWQWNV-----GSN 182
            ....:|::.|  .|||  .||:..|.:|..: |.|.||....:.|:|:|..|::::.     .:.
plant   131 GLGRVWSSAGSCSHIL--EGHSGAISSVALVNSNDAETVTVATASKDRTLRLFKFDPAESVDSTT 193

  Fly   183 SVECVSVCKGHERGVDSVSVSPDGLRFATGSWDTMLKVWSAELDDAVEGSSKRMK---------E 238
            .|....:.:||:..|.|||....|....:.|||..:.:|:.. :...||.|..:|         |
plant   194 KVRAYKILRGHKASVQSVSAQKSGNMVCSSSWDCTINLWNTN-ESTSEGESVSVKKRKGNNQAEE 257

  Fly   239 SGVRTPKIT-LQGHRESVSAVQWMDATTLLTGSWDHTLKVWDLSLEGIKTEISTNKSIFDASY-S 301
            |......:| |.||.:.||:|.|.:...:.:.||||:::.||:........:...|::..... .
plant   258 SQSEGEAVTSLVGHTQCVSSVVWPEHDVIYSSSWDHSVRRWDVETGKDSLNLFCGKALNTVDVGG 322

  Fly   302 KLNRLILTASADKNLRLYDPRTNQGSVVRNTYLGHNAWVQTVMWSTTEEFLFVSGAYDNQNKLWD 366
            :.:.||....:|..||::|||....|.....:..|::|:....|..:..|..:|.:||.:..|||
plant   323 ESSALIAAGGSDPILRVWDPRKPGTSAPVFQFSSHSSWISACKWHKSSWFHLLSASYDGKIMLWD 387

  Fly   367 CRSPKAPLYDLLGHGEKVLDIDWSNPKYIVSGGVDNTVRV 406
            .|: ..||..:..|.:|||..||...:.:||||.|:.:|:
plant   388 LRT-AWPLSVIDTHNDKVLSADWWKGESVVSGGADSNLRI 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6724	NP_609452.1	NLE	10..75	CDD:285380	21/68 (31%)
		WD40	105..>411	CDD:225201	98/322 (30%)
		WD40	105..408	CDD:238121	98/322 (30%)
		WD40 repeat	198..250	CDD:293791	16/61 (26%)
		WD40 repeat	255..288	CDD:293791	10/32 (31%)
		WD40 repeat	296..333	CDD:293791	9/37 (24%)
		WD40 repeat	340..378	CDD:293791	11/37 (30%)
AT5G15550	NP_001332618.1	NLE	12..79	CDD:400462	21/66 (32%)
		WD40	109..426	CDD:238121	97/320 (30%)
		WD40 repeat	154..203	CDD:293791	10/48 (21%)
		WD40 repeat	208..269	CDD:293791	16/61 (26%)
		WD40 repeat	276..310	CDD:293791	9/33 (27%)
		WD40 repeat	315..353	CDD:293791	9/37 (24%)
		WD40 repeat	361..399	CDD:293791	11/38 (29%)
		WD40 repeat	404..426	CDD:293791	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	51	1.000	Domainoid score	I4352
eggNOG	1	0.900	-	-		E1_KOG0313
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10098
Inparanoid	1	1.050	198	1.000	Inparanoid score	I1328
OMA	1	1.010	-	-		QHG53844
OrthoDB	1	1.010	-	-		D1540178at2759
OrthoFinder	1	1.000	-	-		FOG0005032
OrthoInspector	1	1.000	-	-		oto3706
orthoMCL	1	0.900	-	-		OOG6_102659
Panther	1	1.100	-	-	LDO	PTHR19855
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3556
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840