DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc2 and UBE2E2

DIOPT Version :9

Sequence 1:	NP_001260362.1	Gene:	Ubc2 / 34487	FlyBaseID:	FBgn0015320	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001357154.1	Gene:	UBE2E2 / 7325	HGNCID:	12478	Length:	201	Species:	Homo sapiens

Alignment Length:	215	Identity:	153/215 - (71%)
Similarity:	166/215 - (77%)	Gaps:	24/215 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 STTASNVSNTSQPTTAGTPQARGGRGSNANGGASGSNAGG-GDEP--------RKEAKTTPRISR 82
            ||.|..|.::  |:|:|             |.:.|..... ..||        :||.|.:.:.:.
Human     2 STEAQRVDDS--PSTSG-------------GSSDGDQRESVQQEPEREQVQPKKKEGKISSKTAA 51

  Fly    83 ALGTSAKRIQKELAEITLDPPPNCSAGPKGDNLYEWVSTILGPPGSVYEGGVFFLDIHFSPEYPF 147
            .|.|||||||||||||||||||||||||||||:|||.||||||||||||||||||||.|||:|||
Human    52 KLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPF 116

  Fly   148 KPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQY 212
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   117 KPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQY 181

  Fly   213 LQNREEHDRIARLWTKRYAT 232
            :.||.||||:||.|||||||
Human   182 MTNRAEHDRMARQWTKRYAT 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc2	NP_001260362.1	COG5078	86..231	CDD:227410	135/144 (94%)
Ubc2	NP_001260362.1	UQ_con	90..227	CDD:278603	127/136 (93%)
UBE2E2	NP_001357154.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55		15/67 (22%)
UBE2E2	NP_001357154.1	UQ_con	59..196	CDD:395127	127/136 (93%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	271	1.000	Domainoid score	I1821
eggNOG	1	0.900	-	-		E2759_KOG0417
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H77337
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2691
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53976
OrthoDB	1	1.010	-	-		D1337945at2759
OrthoFinder	1	1.000	-	-		FOG0002573
OrthoInspector	1	1.000	-	-		otm40329
orthoMCL	1	0.900	-	-		OOG6_103488
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4811
SonicParanoid	1	1.000	-	-		X1929
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870