DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6495 and spint1b

DIOPT Version :9

Sequence 1:	NP_609451.1	Gene:	CG6495 / 34486	FlyBaseID:	FBgn0027550	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_001104693.1	Gene:	spint1b / 797346	ZFINID:	ZDB-GENE-071218-1	Length:	499	Species:	Danio rerio

Alignment Length:	306	Identity:	68/306 - (22%)
Similarity:	102/306 - (33%)	Gaps:	108/306 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 HFDVHKNTIIRTGESQAIGGKYLQGIELDTIEECERLCCETDACDVYIFERKAG-GYCYLFECGP 113
            |....:|.::.|.||...|..:|....:...:.|...||:...|::.:.|.:|. ..|:||.|..
Zfish    36 HHPGRENFVLHTEESIEAGAVFLANPSVAHEDACMAACCKDARCNLALVENQASDNNCFLFNCLY 100

  Fly   114 PEDFRCKFTRHANYTSAVLN--------------PQPKPVG----ELVTTPRPQLPHIPSNNVS- 159
            ...|.||||....:|:.:|:              ....|:.    ::|..|...:  :.:.|.|
Zfish   101 KHRFVCKFTPKQGFTNYILSSVYEKYLSGRKSEGKDSPPIANAGRDVVVQPNEDV--LLNGNESW 163

  Fly   160 ------QQEWELS--NLKL---KPEARD--------------KPTVSTAA---------VVAPTS 190
                  ..||.|:  |..:   |...||              |.||:.:|         |:..||
Zfish   164 DDKEIVNYEWSLTRGNKSVHMEKTNFRDQIRVSNLIPGVYEFKLTVTDSADQSDSAQVIVLVLTS 228

  Fly   191 G-------TGTGTG----------------------VGLGVGQSPVYQSQS-------------- 212
            .       |...||                      .|..:..|..|.|::
Zfish   229 EQSERHCLTPKKTGPCRASFIRWNYNAASRRCEQFIFGGCMENSNNYLSETECQNACENTTVRAG 293

  Fly   213 -----VP----AAHCGRFQFTCHSGECIAVYNACDGIPQCEDGSDE 249
                 ||    ::.||...|.|.||.|:.....|||..:|.|||||
Zfish   294 GVTRKVPVEDCSSPCGVDSFKCSSGCCVKKEFECDGHQECSDGSDE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6495	NP_609451.1	MANEC	47..129	CDD:284837	22/79 (28%)
CG6495	NP_609451.1	LDLa	218..249	CDD:238060	14/30 (47%)
spint1b	NP_001104693.1	MANEC	31..116	CDD:284837	22/79 (28%)
		PKD	148..225	CDD:214510	16/78 (21%)
		Kunitz_BPTI	235..285	CDD:278443	7/49 (14%)
		LDLa	308..342	CDD:238060	16/32 (50%)
		Kunitz_BPTI	363..413	CDD:278443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12286
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.960