Protein Alignment CG6495 and Lrp11

DIOPT Version :9

• Sequence 1: NP_609451.1
• Gene: CG6495 / 34486
• FlyBaseID: FBgn0027550
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001366080.1
• Gene: Lrp11 / 237253
• MGIID: 2442989
• Length: 488
• Species: Mus musculus
• Alignment Length: 672
• Identity: 128/672 - (19%)
• Similarity: 197/672 - (29%)
• Gaps: 323/672 - (48%)

  Fly    56 NTIIRTGESQAIGGKYLQGI-ELDTIEECERLCCETDACDVYIFERKAG---------GYCYLFE 110
            :|||||.:|.|.|..:|:.. .:....:|...||...:|.|.:.:...|         ..||||.
Mouse    88 DTIIRTQDSIAAGASFLRAPGSVRGWRQCVTACCSEPSCSVAVVQLPRGPSVPAPMPAPRCYLFN 152

  Fly   111 CGPPEDFRCKFTRHANYTSAVLNPQPKPVGELVTTPRPQ-------------LPHIPSNNVSQQ- 161
            |.......|||.....|.:..|:......|   ..|||.             :.|:|::.|...
Mouse   153 CTARGRSVCKFAPLRGYRTYTLSRAEDAAG---IPPRPDEDKPPVSKAGKDVVLHLPTDGVVLDG 214

  Fly   162 ------------EWEL-----SNLKLKPEARDKPTVSTAAV-----------VAPTSGTGTGTGV 198
                        ||.|     |::.:|......|...|..:           :..|...|..:..
Mouse   215 RESSDDHAIVLYEWTLQQGDPSSVDMKLFVWQVPQPGTLRLSRLKEGAYIFQLTVTDSVGQRSSD 279

  Fly   199 GLGVGQSPVYQSQSVPAAHCGRFQFTCHSGECIAVYNACDGIPQCEDGSDEGPECNIVLSTATKP 263
            .:.|...|...|....::.|.|:.|.|.||.||.:..||||:.||.|||||....|:.|
Mouse   280 NVSVTVLPRPYSTGGCSSACSRYHFFCDSGCCIDIALACDGVRQCPDGSDEDFCQNLAL------ 338

  Fly   264 ATTSSNLEPVKPMVSQYVPVQNVQQTQQVVAQQMQQQQPQQQQQQPQQQPQHVIVLGPPPPPPPP 328
                                                                             
Mouse   339 ----------------------------------------------------------------- 338

  Fly   329 PPMVNNREDAAAWANRKMIAEGQQQLPQQQLQQQQQQQSSQPKTEIINTDAQSHIFSHKGGLQLQ 393
                          :||::                        |..:.|.||      .|.:.|.
Mouse   339 --------------DRKLV------------------------THTVATSAQ------PGAMGLN 359

  Fly   394 QPANGQGPPPSPLQVPGQMAGAGQVQVQGQSPTLQLPGYEANQAVYGMSRTGIYMPQQPAQLQAP 458
            :   |:|.|              :::...::.|                      ..|||.:..|
Mouse   360 E---GEGDP--------------KLEKSQRATT----------------------HNQPATVSHP 385

  Fly   459 AGQQQQQVQASVVWPQQAPLIPQQQSPVQQSQSLMPQQSGHVYAAAAPAIQSPPAAQQAMLPVLN 523
                :.::.::    |:||  ..|.:|||                                |..|
Mouse   386 ----ETRIHST----QKAP--ESQINPVQ--------------------------------PDSN 408

  Fly   524 AAPVAGKNQGPAADGDYDDYDEETYTEAPKKKQHKHKKVKTKTAKDPIELALEQNKLQPEGSLPA 588
            :   :||||   .:|:||                    :|:|:.             |..|..||
Mouse   409 S---SGKNQ---EEGNYD--------------------LKSKSG-------------QAGGEHPA 434

  Fly   589 LPVPASPVHEQYKMIHDNLAMEFRDHDGHSERPGGAVLSLTLGLLVTAALAILIGCRMRTVTRRA 653
               |.:                            ||||.|.|||.:|..|.:::.||:|.|.::.
Mouse   435 ---PEA----------------------------GAVLPLALGLAITVLLLLMVTCRLRLVKQKL 468

  Fly   654 RRLGGKTPYSQEADFLVNGMYL 675
            ::....|  |:|:|:|:|||||
Mouse   469 KKARPIT--SEESDYLINGMYL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6495	NP_609451.1	MANEC	47..129	CDD:284837	24/82 (29%)
		LDLa	218..249	CDD:238060	17/30 (57%)
Lrp11	NP_001366080.1	MANEC	69..172	CDD:129004	24/83 (29%)
		PKD	191..285	CDD:214510	13/93 (14%)
		LDLa	299..333	CDD:238060	19/33 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	351..433		32/207 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005567
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46876
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5879
SonicParanoid	1	1.000	-	-		X5981
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	6.000