Protein Alignment CG6495 and LOC1278070

DIOPT Version :10

• Sequence 1: NP_609451.1
• Gene: CG6495 / 34486
• FlyBaseID: FBgn0027550
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_061516387.1
• Gene: LOC1278070 / 1278070
• VectorBaseID: AGAMI1_002171
• Length: 839
• Species: Anopheles gambiae
• Alignment Length: 895
• Identity: 290/895 - (32%)
• Similarity: 374/895 - (41%)
• Gaps: 305/895 - (34%)

  Fly     6 ALPFLLMIAEAAATAEQVKYLEYLQSSPAEHRLSKRMDLEVCIG-HFDVHKNTIIRTGESQAIGG 69
            |.|.||::...|..   |.|...:........::|||::|.|:. .||||.||||||.||:::|.
Mosquito    25 ATPLLLLLFLLATV---VPYHGTIALPEGTFPVAKRMNIETCLAVRFDVHLNTIIRTEESRSMGA 86

  Fly    70 KYLQGIELDTIEECERLCCETDACDVYIFERKAGGYCYLFECGPPEDFRCKFTRHANYTSAVLNP 134
            ::|...:|::.|:|.||||||:.|||::||.|:.|.|:||:|||||:||||||||:|||||||:.
Mosquito    87 RFLDDADLNSREQCLRLCCETENCDVFVFEEKSPGTCFLFQCGPPENFRCKFTRHSNYTSAVLSI 151

  Fly   135 QPKPVGELVTTPRPQL----------PHIPSNN-----VSQQEWELSNLKLKPEARDKPTVSTAA 184
            .|.|:.:  ..|.|.|          |...|:|     :||.|.||.:||.......|...|.
Mosquito   152 PPPPMEQ--PPPPPPLAAQIQSLAGQPATTSSNGATKPLSQHELELVSLKDGGGTNGKQIGSN-- 212

  Fly   185 VVAPTSGTGTGTGVGLGVGQSPVYQSQSVP------AAHCGRFQFTCHSGECIAVYNACDGIPQC 243
             :|..|.|.....:|:.:|:.|...|.|.|      |..||.|:|.|||||||||||.|||||||
Mosquito   213 -LASASSTTPLPPLGVRLGELPTTPSASTPKQAAAVAQQCGHFEFPCHSGECIAVYNVCDGIPQC 276

  Fly   244 EDGSDEGPEC---NIVLSTATKPATTSSNLE---------------------------------- 271
            |||||||.||   |......:.|.......|
Mosquito   277 EDGSDEGAECPQKNDRAPLVSSPGVLQQGREQGAGLGNVNGGGSVNQPIMMIPSVRGGAGGNTPL 341

  Fly   272 --PVKPMVSQ--YVPVQNVQQTQQVVAQQMQQQQPQQQQQQPQQQPQHVIVLGPPPPPPP-PPPM 331
              |.:.||.|  |.|: :.||.....:..::||  ||||||..:|..|.....|...|.| |.|.
Mosquito   342 GMPSQGMVGQGIYQPL-DFQQPPNRFSLSLEQQ--QQQQQQLTKQIMHRNREDPMTAPKPWPRPA 403

  Fly   332 VNNREDAAAWANRKMIAEGQQQLPQQQLQQQQQQQSSQPKTEIINTDAQSHIFSHKGGLQLQQPA 396
            :|                                     :...::| :.||||:||||||| .|.
Mosquito   404 IN-------------------------------------EPNYVDT-SDSHIFNHKGGLQL-SPI 429

  Fly   397 NGQGPP--------PSPLQVPGQ--MAGAGQVQVQGQSPTLQLPGYEANQAVYGMSRTGIYMPQQ 451
            ||.||.        |.|..:|..  :.|.|     |....|.|||...             .|||
Mosquito   430 NGLGPASQQYQESLPEPNYMPSSSVIRGGG-----GGKSYLTLPGSSG-------------YPQQ 476

  Fly   452 PAQLQAPAGQQQQQVQASVV----------------WPQQ-------------APLIPQQ---QS 484
            |.| |.|..|.||...:|..                ||.|             ||  ||:   |.
Mosquito   477 PLQ-QFPPEQPQQLPPSSYKSILPSQWMGSNSVRSNWPMQPGDGLPSGGGSDGAP--PQEQYIQP 538

  Fly   485 PVQ------------------------QSQSLMPQQSGHVYAAA--------------------- 504
            |||                        |.||::.|.:.|...|.
Mosquito   539 PVQQHRPVMQELQSTSNGADAASSITMQQQSVINQPAAHPSGAQWGLGSQTAGGGATPTPNAVVP 603

  Fly   505 --------------------APAIQSPPAAQQAMLPVLNA-APVAGKNQGPAAD--GDYDDYDEE 546
                                .||..:.||.....||...| ||.:.|::.||::  |...:|:|:
Mosquito   604 GAPAAPGAAGEESNNRAGSDTPAANNNPAPGHESLPASGATAPDSAKHKPPASNPSGGGAEYEED 668

  Fly   547 TY----------------------TEAPKK---KQHKH-------------------------KK 561
            .|                      ||.|||   |.|||                         ||
Mosquito   669 AYEDTYPESTNAAGGEEQSQPPTQTEPPKKKLRKHHKHGKQGAAASDSDLDTANEQQTEQQQKKK 733

  Fly   562 VKTKTAKDPIELALEQNKLQPEGSLPALPVPASP-VHEQYKMIHDNLAMEFRDHDGHSERPGGAV 625
            .||||.|        ::|....|:.........| |||..|.:|.:|.:||.||||:::|||||:
Mosquito   734 KKTKTIK--------KDKAADHGAGSGHHAGTDPIVHEHLKALHKDLEIEFADHDGYADRPGGAM 790

  Fly   626 LSLTLGLLVTAALAILIGCRMRTVTRRARRLGGKTPYSQEADFLVNGMYL 675
            ||||||:|:|||:.||:.||||...||.|| .||:.|:.:||||||||||
Mosquito   791 LSLTLGVLLTAAMGILLSCRMRVARRRIRR-PGKSSYAHDADFLVNGMYL 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6495	NP_609451.1	MANEC	42..130	CDD:129004	52/88 (59%)
		LDLa	218..249	CDD:238060	26/30 (87%)
LOC1278070	XP_061516387.1	None