DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12299 and LOC557537

DIOPT Version :9

Sequence 1:	NP_609448.1	Gene:	CG12299 / 34483	FlyBaseID:	FBgn0032295	Length:	736	Species:	Drosophila melanogaster
Sequence 2:	XP_009301868.1	Gene:	LOC557537 / 557537	-ID:	-	Length:	393	Species:	Danio rerio

Alignment Length:	332	Identity:	109/332 - (32%)
Similarity:	160/332 - (48%)	Gaps:	29/332 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 RRRGRRSNIGAPVMDPALNGNQKCFQCTHCEASFPNAGDLSKHVRSHITNKPFQCSICQKTFTHI 294
            ::|.:||.            .:|.|.|..|..||.....|..|.|.|...||:.|..|.|:|:..
Zfish    74 QKRTQRSR------------GEKSFICQQCGKSFRQRKQLKIHTRIHTGEKPYSCQECGKSFSQS 126

  Fly   295 GSLNTHIRIHSGEKPYKCELCPKAFTQSSSLMVHMRSHSVRKPHQCVQCDKGFINYSSLLLHQKT 359
            .:...|:||||||||:.||.|.|:|.|..:|:.|.|.|:..||:.|..|.|.|...:.|.:|.:.
Zfish   127 SARKVHMRIHSGEKPFTCEQCGKSFRQKKNLVGHRRIHTGEKPYTCTLCGKSFSQVAGLEIHMRI 191

  Fly   360 HIAPTETFICPECEREFKAEALLDEHMRMHTQELVYQCAICREAFRASSELVQHMKNHMGEKPFT 424
            |.. .:.|.|.||.:.|.::..|..||.:|:.|.::.|..|..:|.......:|:..|..|:|||
Zfish   192 HTG-EKPFTCQECGKSFNSKETLKCHMTVHSGEKIFTCKPCGISFTQKVSFKKHVLVHNSEQPFT 255

  Fly   425 CSLCDRSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFTQASSLSVHMKIHAGEKPYPCPICGKSYS 489
            ||.|.:||.|...|.:|:|:|:.||.|.|..|.|.|........||:||.||:||.||.|||::|
Zfish   256 CSQCGKSFDQEEHLKVHIRVHSKEKRFTCSTCGKGFYDKQRFEDHMRIHNGEQPYTCPHCGKTFS 320

  Fly   490 QQAYLNKHIQAHQMASAASAS------TSPGLL-------VAKQPHETLVCIVCGSLHADATALA 541
            .:..:|.|::.|....:.:..      ...|.|       ..::|..   |..||......:.|.
Zfish   321 YKKNMNAHMRIHTEERSFTCDQCGKDFNQIGHLNIHMRVHTGERPFR---CGHCGKSFKHDSGLK 382

  Fly   542 SHVHSQH 548
            .|:::.|
Zfish   383 YHMNTAH 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	<254..413	CDD:227381	56/158 (35%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..293	CDD:290200	10/24 (42%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..321	CDD:290200	14/24 (58%)
		zf-C2H2_2	312..>387	CDD:289522	26/74 (35%)
		C2H2 Zn finger	312..332	CDD:275368	9/19 (47%)
		C2H2 Zn finger	340..360	CDD:275368	6/19 (32%)
		C2H2 Zn finger	369..389	CDD:275368	7/19 (37%)
		C2H2 Zn finger	397..417	CDD:275368	4/19 (21%)
		zf-H2C2_2	409..434	CDD:290200	11/24 (46%)
		C2H2 Zn finger	425..445	CDD:275368	9/19 (47%)
		zf-H2C2_2	437..462	CDD:290200	11/24 (46%)
		C2H2 Zn finger	453..473	CDD:275368	6/19 (32%)
		zf-H2C2_2	465..490	CDD:290200	13/24 (54%)
		C2H2 Zn finger	481..501	CDD:275368	8/19 (42%)
LOC557537	XP_009301868.1	COG5048	62..>379	CDD:227381	106/320 (33%)
		C2H2 Zn finger	88..108	CDD:275368	7/19 (37%)
		zf-H2C2_2	101..125	CDD:290200	10/23 (43%)
		C2H2 Zn finger	116..136	CDD:275368	6/19 (32%)
		zf-H2C2_2	130..153	CDD:290200	14/22 (64%)
		C2H2 Zn finger	144..164	CDD:275368	9/19 (47%)
		zf-H2C2_2	156..181	CDD:290200	10/24 (42%)
		C2H2 Zn finger	172..192	CDD:275368	6/19 (32%)
		zf-H2C2_2	185..209	CDD:290200	8/24 (33%)
		C2H2 Zn finger	200..220	CDD:275368	7/19 (37%)
		C2H2 Zn finger	228..248	CDD:275368	4/19 (21%)
		C2H2 Zn finger	256..276	CDD:275368	9/19 (47%)
		FYDLN_acid	280..>319	CDD:302856	19/38 (50%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		zf-C2H2	310..332	CDD:278523	9/21 (43%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		C2H2 Zn finger	340..360	CDD:275368	2/19 (11%)
		zf-H2C2_2	352..377	CDD:290200	5/27 (19%)
		C2H2 Zn finger	368..387	CDD:275368	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910