Protein Alignment CG12299 and LOC4576068

DIOPT Version :10

• Sequence 1: NP_609448.1
• Gene: CG12299 / 34483
• FlyBaseID: FBgn0032295
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: XP_001237313.4
• Gene: LOC4576068 / 4576068
• VectorBaseID: AGAMI1_004786
• Length: 533
• Species: Anopheles gambiae
• Alignment Length: 486
• Identity: 100/486 - (20%)
• Similarity: 162/486 - (33%)
• Gaps: 139/486 - (28%)

  Fly    86 GDESEDYSWIFEPVCE----------------LAEDGSDSSDGS--------ASSGSDSSSSSDD 126
            ||.:.|.:.:....||                :..:|....:||        ...|.......:.
Mosquito    95 GDWASDSNRVLLRECENFIVRHKQQVDYLYASIVSEGEQYLEGSLEIERELFGGEGQQEEHLEEH 159

  Fly   127 DDDDDDDDSSSSSSSSSNSSSSSSSVPTTSNSNTQQSQESVQPLHGLVAGPGYNEFQLQMTDPRE 191
            ..:...|:                 |..||.|.|::              ||....:|:..:|
Mosquito   160 QQEQQQDE-----------------VDKTSGSETRR--------------PGPQSGRLEQCEP-- 191

  Fly   192 STSIFMVQPTVSVTPLQQLLPPAPTVSPGLGLQSTPIKRRRGRRSNIGAPVMD------------ 244
                   .|.:.:...:.|....|.:..|..|.:|.....:.||..:...:.|
Mosquito   192 -------DPEILLEITKFLEEQTPRLPDGGRLDATEHVVEQRRRCGLCCVLSDVTLELTSDQLKA 249

  Fly   245 -PALNGNQKCFQCTHC---------------------------------EASFPNAGDLSKHVR- 274
             .|||.::....|..|                                 :::...|..|:..:|
Mosquito   250 LGALNVDKTPQVCEECCILLDIVDSFRKTTTIARELSGQEQRALDVLQLDSALEQAKCLASKLRH 314

  Fly   275 SHITNKPFQCSICQKTFTHIGSLNTHIRIHS-------GEKPYK-----CELCPKAFTQSSSLMV 327
            .|......|||        .||::......|       ..|.||     |.:|.|.: .|..|..
Mosquito   315 KHDAFAGLQCS--------GGSMDASSTTSSPAERQSVPRKAYKRAKVTCHICGKQY-DSWKLQT 370

  Fly   328 HMRSHSVRKPHQCVQ--CDKGFINYSSLLLHQKTHIAPTETF--ICPECEREFKAEALLDEHMRM 388
            |:..|...:|:.|.|  |...|.....|..|:|  :..|:.|  :|..|.::.|.:.:...|:..
Mosquito   371 HLNEHENIRPYVCDQEGCSSTFAGLVLLNRHKK--LWHTDYFYAVCNVCGKKCKTQGIYKTHLSY 433

  Fly   389 HTQELVYQCAICREAFRASSELVQHMKNHMGEKPFTCSLCDRSFTQSGSLNIHMRIHTGEKPFQC 453
            | :|....|.:|.:..|....:.:|||.|..::...|.:|::.||.:.:|.:||||||.:||:.|
Mosquito   434 H-EEPKLPCTVCGKLMRNKRAIWKHMKTHSNDRKHVCGVCNKRFTIAYTLRVHMRIHTNDKPYPC 497

  Fly   454 KLCDKCFTQASSLSVHMKIHAGEKPYPCPIC 484
            ..|||.|.....|..|.:.:.|....|.|.|
Mosquito   498 ADCDKRFQYKCLLKNHCRRYHGGGNEPAPPC 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	245..>501	CDD:227381	72/290 (25%)
		C2H2 Zn finger	256..276	CDD:275368	5/53 (9%)
		C2H2 Zn finger	284..304	CDD:275368	4/19 (21%)
		zf-H2C2_2	296..321	CDD:463886	8/36 (22%)
		C2H2 Zn finger	312..332	CDD:275368	6/19 (32%)
		C2H2 Zn finger	340..360	CDD:275368	7/21 (33%)
		C2H2 Zn finger	369..389	CDD:275368	4/19 (21%)
		C2H2 Zn finger	397..417	CDD:275368	6/19 (32%)
		zf-H2C2_2	409..434	CDD:463886	7/24 (29%)
		C2H2 Zn finger	425..445	CDD:275368	8/19 (42%)
		zf-H2C2_2	437..462	CDD:463886	14/24 (58%)
		C2H2 Zn finger	453..473	CDD:275368	7/19 (37%)
		C2H2 Zn finger	481..501	CDD:275368	2/4 (50%)
LOC4576068	XP_001237313.4	None