Protein Alignment CG12299 and su(Hw)

DIOPT Version :10

• Sequence 1: NP_609448.1
• Gene: CG12299 / 34483
• FlyBaseID: FBgn0032295
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_524349.1
• Gene: su(Hw) / 41740
• FlyBaseID: FBgn0003567
• Length: 941
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 153/673 - (22%)
• Similarity: 260/673 - (38%)
• Gaps: 141/673 - (20%)

  Fly   115 SSGSDSSSSSDDDD-DDDDDDSSSSSSSSSNSSSSSSSVPTTSNSNTQQSQESVQPLHGLVAGPG 178
            ::|.:...:.||:| .:|.|:....||...||                 ||..::.:...|.|..
  Fly   178 NNGQEIVVTEDDEDLGEDGDEDGEDSSGKGNS-----------------SQTKIKEIVEHVCGKC 225

  Fly   179 YNEFQLQMTDPRESTSIFMVQPTVSVTPLQQLLPPAPTVSPGLGLQSTPIKRRRGRRSNIGAPVM 243
            |..|:                   .|..|::.|... ....|..|:...:.:.. .:....|.||
  Fly   226 YKTFR-------------------RVQSLKKHLEFC-RYDSGYHLRKADMLKNL-EKIEKDAVVM 269

  Fly   244 DPALNGNQKCF--------------QCTHCEASFPNAGDLSKHV-RSHITNKPFQCSICQKTFTH 293
            :.    ...||              .|..|..||.......:|: .:|.....|.||||......
  Fly   270 EK----KDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANLRS 330

  Fly   294 IGSLNTHIRIH-SGEKPYKCELCPKAFTQSSSLMVHMR----SHSVRKPHQCVQCDKGFINYSSL 353
            ...|..|...| |..|||.|::|.|.||:|..|..|.:    |.:......|..||:.|....:|
  Fly   331 EALLALHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNL 395

  Fly   354 LLHQKTH----IAPTETFICPECEREFKAEALLDEHMRMHTQELVYQCAICREAFRASSELVQHM 414
            ..|.|.|    :.....::|..|:..|.:.:.|:.|:|.||.|..:.|.:|.:.|.|...|.:|.
  Fly   396 RSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHR 460

  Fly   415 KNHMGEKPFTCSLCDRSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFTQASSLSVHMKIHAGEKPY 479
            :.|.||||::|::|:::|.....||.||:.||||:|.:|..|.|.|.||:.|..|.|.|.  :|:
  Fly   461 RYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSKTHI--RPF 523

  Fly   480 PCPICGKSYSQQAYLNKHIQAHQMASAASASTSPGLLVAKQPHETLVCIVCGSLHADATALASHV 544
            ||..|.:.:..:..|.:|::.|..              .|:|  ...|..|.........|..|:
  Fly   524 PCEQCDEKFKTEKQLERHVKTHSR--------------TKRP--VFSCAECKRNFRTPALLKEHM 572

  Fly   545 -HSQHAALLDTMKQSGMNTAPGGAIPDVKCSAEEQQAYVERVQCVLQQMNHQ-----QQHQQ--H 601
             ..:|:   ...::|.|.:|       ||        .:||..|.:...|..     ::|.:  |
  Fly   573 DEGKHS---PKQQRSSMRSA-------VK--------IMERTDCAICDKNFDSSDTLRRHIRTVH 619

  Fly   602 QQQPPQ--QQQQHPQQQQQQHLQQQPHQMQLPQQPKLPAMDSTGED----------EEEPDEAEE 654
            :..|..  ..:.||.::.::.::.: ..:.:.......::.|:..|          .:|.|.|.:
  Fly   620 ECDPDDIFGVEPHPSKRAKKDIESE-EVVPVALNTSAGSLISSQTDGNGVVVREFLVDEGDGAAQ 683

  Fly   655 ------------PPDEEEEQDEPEEPAEVKTEVLAAEDALTNPGYPILGLQEEQILLDSDMYYED 707
                        |.|...|.::..:.|.||.|. ..|:|..:|    :..:|::..|.:.:....
  Fly   684 TITLENETYTILPLDGAIEGEQLTDEAGVKPEA-KKEEAQVSP----VVKKEQRKSLAASLAAAI 743

  Fly   708 FGDMDVGCQEEVFGDFVVNEEEV 730
            ..:::..|.|:.|...::.||::
  Fly   744 ADNLEESCSEDDFSGEILTEEDI 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	245..>501	CDD:227381	85/279 (30%)
		C2H2 Zn finger	256..276	CDD:275368	5/20 (25%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..321	CDD:463886	11/25 (44%)
		C2H2 Zn finger	312..332	CDD:275368	8/23 (35%)
		C2H2 Zn finger	340..360	CDD:275368	7/19 (37%)
		C2H2 Zn finger	369..389	CDD:275368	6/19 (32%)
		C2H2 Zn finger	397..417	CDD:275368	6/19 (32%)
		zf-H2C2_2	409..434	CDD:463886	10/24 (42%)
		C2H2 Zn finger	425..445	CDD:275368	7/19 (37%)
		zf-H2C2_2	437..462	CDD:463886	13/24 (54%)
		C2H2 Zn finger	453..473	CDD:275368	9/19 (47%)
		C2H2 Zn finger	481..501	CDD:275368	4/19 (21%)
su(Hw)	NP_524349.1	C2H2 Zn finger	292..313	CDD:275368	5/20 (25%)
		COG5048	<312..517	CDD:227381	70/204 (34%)
		C2H2 Zn finger	321..341	CDD:275368	6/19 (32%)
		C2H2 Zn finger	350..368	CDD:275368	8/17 (47%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..435	CDD:275368	6/19 (32%)
		C2H2 Zn finger	443..463	CDD:275368	6/19 (32%)
		COG5048	<467..620	CDD:227381	48/188 (26%)
		C2H2 Zn finger	471..491	CDD:275368	7/19 (37%)
		C2H2 Zn finger	499..519	CDD:275368	9/19 (47%)
		C2H2 Zn finger	525..545	CDD:275368	4/19 (21%)
		C2H2 Zn finger	555..572	CDD:275368	3/16 (19%)
		C2H2 Zn finger	598..615	CDD:275371	2/16 (13%)