DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12299 and Zfp523

DIOPT Version :9

Sequence 1:NP_609448.1 Gene:CG12299 / 34483 FlyBaseID:FBgn0032295 Length:736 Species:Drosophila melanogaster
Sequence 2:NP_001128227.1 Gene:Zfp523 / 361809 RGDID:1306239 Length:568 Species:Rattus norvegicus


Alignment Length:468 Identity:128/468 - (27%)
Similarity:186/468 - (39%) Gaps:110/468 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 GYNEFQLQMTDPRESTSIFMVQPTVSVTPLQQLLPPAPTVSPGLGLQSTPIKRRRGRRSNIGAPV 242
            ||:...|:.....:.::.::..| |||.|...:|    .|...:||:....:...|    .||  
  Rat    79 GYDPSALEAVQLEDGSTAYIHHP-VSVPPDSTIL----AVQTEVGLEDLAAEEEEG----FGA-- 132

  Fly   243 MDPALNGNQKCFQCTH-CEASFPNAGDLSKHVRSHITNKPFQCSI--CQKTFTHIGSLNTHIRIH 304
             |..:...|...:..| ..||....|       ..:.::.|:|..  |.:.:|....|..|.|.|
  Rat   133 -DTVVALEQYASKVLHDSPASHNGKG-------QQVGDRAFRCGYKGCGRLYTTAHHLKVHERAH 189

  Fly   305 SGEKPYKCEL--CPKAFTQSSSLMVHMRSHSVRKPHQCVQCDKGFINYSSLLLHQKTHIAPTETF 367
            :|::.|:|:.  |.|||.....|..|:|:|:..||::|                      |.|. 
  Rat   190 TGDRSYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKC----------------------PEEL- 231

  Fly   368 ICPECEREFKAEALLDEHMRMHTQELVYQCAI--CREAFRASSELVQHMKNHMGEKPFTC--SLC 428
                |.:.||....|.:|:|.||.|..::|..  |..:|..|:....|::.|.||:|:||  ..|
  Rat   232 ----CSKAFKTSGDLQKHVRTHTGERPFRCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHC 292

  Fly   429 DRSFTQSGSLNIHMRIHTGEKPFQCKL--CDKCFTQASSLSVHMKIHAGEKPYPCPICGKSYSQQ 491
            .|.||.:.:...|:||||||||:.|.:  |.|.||:.|||..|..:|...|||.|..|||:|.|.
  Rat   293 GRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSSCGKTYRQT 357

  Fly   492 AYLNKHIQ-AH-------------------QMASAASASTSPGLLVAKQPHETLVCIVCGSLHAD 536
            :.|..|.: ||                   :.||||..|.||     |..|              
  Rat   358 STLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPSP-----KPTH-------------- 403

  Fly   537 ATALASHVHSQHAALLDTMKQSGMNTAPGGA----------IPDVKCSAEEQQAYVERVQCVLQQ 591
             .|..|.|..:.:   |...|..|.|...||          ...|..|.|:.||....:..|.|.
  Rat   404 -IAYLSEVKEESS---DIPTQVAMVTEEDGAPQVALITQDGTQQVSLSPEDLQALGSAISVVTQH 464

  Fly   592 MNHQQQHQQHQQQ 604
            .:.......||::
  Rat   465 RSTTLTIPGHQEE 477

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12299NP_609448.1 COG5048 <254..413 CDD:227381 41/165 (25%)
C2H2 Zn finger 256..276 CDD:275368 4/20 (20%)
zf-H2C2_2 268..293 CDD:290200 3/26 (12%)
C2H2 Zn finger 284..304 CDD:275368 6/21 (29%)
zf-H2C2_2 296..321 CDD:290200 11/26 (42%)
zf-C2H2_2 312..>387 CDD:289522 19/76 (25%)
C2H2 Zn finger 312..332 CDD:275368 8/21 (38%)
C2H2 Zn finger 340..360 CDD:275368 1/19 (5%)
C2H2 Zn finger 369..389 CDD:275368 6/19 (32%)
C2H2 Zn finger 397..417 CDD:275368 5/21 (24%)
zf-H2C2_2 409..434 CDD:290200 10/26 (38%)
C2H2 Zn finger 425..445 CDD:275368 7/21 (33%)
zf-H2C2_2 437..462 CDD:290200 13/26 (50%)
C2H2 Zn finger 453..473 CDD:275368 9/21 (43%)
zf-H2C2_2 465..490 CDD:290200 12/24 (50%)
C2H2 Zn finger 481..501 CDD:275368 8/20 (40%)
Zfp523NP_001128227.1 3 X 12 AA approximate repeats 34..99 3/19 (16%)
C2H2 Zn finger 167..189 CDD:275368 6/21 (29%)
zf-H2C2_2 181..208 CDD:290200 11/26 (42%)
COG5048 192..>257 CDD:227381 24/91 (26%)
C2H2 Zn finger 197..219 CDD:275368 8/21 (38%)
zf-H2C2_2 212..238 CDD:290200 11/52 (21%)
zf-C2H2_aberr 225..346 CDD:293622 48/147 (33%)
C2H2 Zn finger 227..249 CDD:275368 9/48 (19%)
zf-H2C2_2 241..268 CDD:290200 9/26 (35%)
C2H2 Zn finger 257..279 CDD:275368 5/21 (24%)
zf-H2C2_2 273..298 CDD:290200 10/24 (42%)
C2H2 Zn finger 287..309 CDD:275368 7/21 (33%)
zf-H2C2_2 301..327 CDD:290200 12/25 (48%)
C2H2 Zn finger 317..339 CDD:275368 9/21 (43%)
C2H2 Zn finger 347..365 CDD:275368 8/17 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 365..401 9/40 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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