Protein Alignment CG12299 and erm

DIOPT Version :10

• Sequence 1: NP_609448.1
• Gene: CG12299 / 34483
• FlyBaseID: FBgn0032295
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_001259891.2
• Gene: erm / 326152
• FlyBaseID: FBgn0031375
• Length: 698
• Species: Drosophila melanogaster
• Alignment Length: 694
• Identity: 153/694 - (22%)
• Similarity: 230/694 - (33%)
• Gaps: 196/694 - (28%)

  Fly    12 LPLTITPILQQTHLLPQQAPNPPQQQPQQPQPPDLTFHCMCCAEFFVHPLALYQHMNTLHP-HEP 75
            :|.:.:|:::..    ....||.||..||.:.   :....|..:|.:..:        :.| |.|
  Fly    21 MPPSKSPVMESA----ASEQNPAQQSQQQDEQ---SAKRACPLKFSIAKI--------MEPDHRP 70

  Fly    76 GNGQQEQESP-----GDESEDYSWIFEPVCELAEDGSDSSDGSASSGSDSSSSSDDDDDDDDDDS 135
            ......|.:|     .|:.||            ||....:|...|.......|.|......:.||
  Fly    71 SQVPPPQPAPVSFATNDDDED------------EDPEIDADSERSCSPIEVISLDQSPSTVNYDS 123

  Fly   136 SSSS---SSSSNSSSSSSSVPTTSN-----SNTQQSQESVQPL---------------------- 170
            :...   ...|.::||.:|.|:|:.     |:..|...|..||
  Fly   124 AFKKYVPGPCSGATSSVASPPSTAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTA 188

  Fly   171 --HGLVAGPGYNEFQLQMTDP---------------RESTSIFMVQPTVSVTPLQQLL---PPAP 215
              ..|.:....:.|...:...               ..:.::..|..:.:|..||..|   |.|.
  Fly   189 QQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHPLAAAAAVAAVAQSQAVPNLQHTLEKSPVAQ 253

  Fly   216 TVSPGLGLQSTPIKRRRGRR--------------SNIGAPVMDPALNGNQKCFQCTHCEASFPNA 266
            ..:...|||:. :||:|..:              |..||....|:..|:        .|.|.|.:
  Fly   254 RTAQSSGLQAN-LKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGS--------IEDSSPGS 309

  Fly   267 GDLSKHVRSHITNKPFQCSICQKTFTHIGSLNTHIRIHSGEKPYKCELCPKAFTQSSSLMVHMRS 331
            ....|       .|.|.|..|.|.|....:|..|:.:|:|.:|:.|::|.|.|.|:|:|..|...
  Fly   310 ASGGK-------PKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKII 367

  Fly   332 HSVRKPHQCVQCDKGFINYSSLLLHQKTHIAPTETFICPECEREFKAEALLDEHMRMHTQELVYQ 396
            |:..|||:|..|.|
  Fly   368 HTSEKPHKCQTCGK--------------------------------------------------- 381

  Fly   397 CAICREAFRASSELVQHMKNHMGEKPFTCSLCDRSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFT 461
                  ||..||.|..|.:.|.|.|||.|..|.:.|.|.|:...|...|:|||.::|.:|:|.|.
  Fly   382 ------AFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFH 440

  Fly   462 QASSLSVHMKIHAGEKPYPCPICGKSYSQQAYLNKHI-QAHQMASAASASTSPGLLVAKQPHETL 525
            |..:|:.||..|..:|||.|.:|.|.:.:...|.||: :.|::.........|.....::.:...
  Fly   441 QVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHEIGGDLDDLDMPPTYDRRREYTRR 505

  Fly   526 VCIVCGSLHADATALASHVHSQHAALLDTMKQSGMNTAPGGAIPDVKCSAEEQQAYVERVQCVLQ 590
            ..:..|             :.|.:..|.....||..:.|.........|.|.......|  ..:.
  Fly   506 EPLASG-------------YGQASGQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPR--SAVS 555

  Fly   591 QMNHQQQHQQHQQQPP----------QQQQQHPQQQQQQHLQQQ 624
            |......|.|....||          |.|.|.|..|.|||.|||
  Fly   556 QYPPGGFHHQLGVAPPHDYPSGSAFLQLQPQQPHPQSQQHHQQQ 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	245..>501	CDD:227381	71/256 (28%)
		C2H2 Zn finger	256..276	CDD:275368	4/19 (21%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..321	CDD:463886	9/24 (38%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		C2H2 Zn finger	340..360	CDD:275368	3/19 (16%)
		C2H2 Zn finger	369..389	CDD:275368	0/19 (0%)
		C2H2 Zn finger	397..417	CDD:275368	6/19 (32%)
		zf-H2C2_2	409..434	CDD:463886	10/24 (42%)
		C2H2 Zn finger	425..445	CDD:275368	6/19 (32%)
		zf-H2C2_2	437..462	CDD:463886	9/24 (38%)
		C2H2 Zn finger	453..473	CDD:275368	8/19 (42%)
		C2H2 Zn finger	481..501	CDD:275368	6/20 (30%)
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	65/237 (27%)
		C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)
		C2H2 Zn finger	348..368	CDD:275368	8/19 (42%)
		zf-H2C2_2	363..385	CDD:463886	10/78 (13%)
		C2H2 Zn finger	376..396	CDD:275368	9/76 (12%)
		C2H2 Zn finger	404..424	CDD:275368	6/19 (32%)
		C2H2 Zn finger	432..452	CDD:275368	8/19 (42%)
		C2H2 Zn finger	460..478	CDD:275368	6/17 (35%)