DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12299 and Zbtb14

DIOPT Version :9

Sequence 1:NP_609448.1 Gene:CG12299 / 34483 FlyBaseID:FBgn0032295 Length:736 Species:Drosophila melanogaster
Sequence 2:NP_001343211.1 Gene:Zbtb14 / 22666 MGIID:1195345 Length:449 Species:Mus musculus


Alignment Length:449 Identity:109/449 - (24%)
Similarity:159/449 - (35%) Gaps:139/449 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 EPVCELAEDGS--DSSDGSASSG---------SDSSSSSDDDDD---DDDDDSSSSSSSSSNSSS 147
            :.:|....|.|  |.|:|.:.|.         .|::.:.|||.:   |.||..|..:...:..|.
Mouse   121 DKLCSQKRDVSSPDESNGQSKSKYCLKLNRPIGDAADAQDDDVEEIGDQDDSPSDDTVEGTPPSQ 185

  Fly   148 SSSSVPTTSNSNTQQSQESVQPLHGLVAGPGYNEFQLQMTDPRESTSIFMVQPTVSVTPLQQLLP 212
            .....|||    |.:.||::  |..|    |..|.:......:|..|:    .|.....|....|
Mouse   186 EDGKSPTT----TLRVQEAI--LKEL----GSEEVRKVNCYGQEVESM----ETPESKDLGSQTP 236

  Fly   213 PAPTVSPGLGL---QSTPIKRRRGRRSNIGAPVMDPALNG-NQKCFQCTHCEASFPNAGDLSKHV 273
            .|.|.:.|:..   :.||     |..:.......:..|.| :::...|..|..:|.:.|.|.||.
Mouse   237 QALTFNDGMSEVKDEQTP-----GWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHE 296

  Fly   274 RSHITNKPFQCSICQKTFTHIGSLNTHIRIHSGEKPYKCELCPKAFTQSSSLMVHMRSHSVRKPH 338
            :.|..::||.|.:|.|.||....|..|::||:|.|||.||:|.|:|.::..|..|.|.||     
Mouse   297 KLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHS----- 356

  Fly   339 QCVQCDKGFINYSSLLLHQKTHIAPTETFICPECEREFKAEALLDEHMRMHTQELVYQCAICREA 403
                                                                             
Mouse   357 ----------------------------------------------------------------- 356

  Fly   404 FRASSELVQHMKNHMGEKPFTCSLCDRSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFTQASSLSV 468
                           .|:||.|.:||::|.....|..|.|.|.|||||.|..|.|.|.:||.|..
Mouse   357 ---------------NERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKR 406

  Fly   469 HMKIHAGEKPYPCPICGKSYSQQAYLNKHIQAHQMASAASASTSPGLLVAKQPHETLVC 527
            |......|:....|...:|.::|      :||..||:.           |:|..||:.|
Mouse   407 HENNMHSERKQVTPSAIQSETEQ------LQAAAMAAE-----------AEQQLETIAC 448

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12299NP_609448.1 COG5048 <254..413 CDD:227381 33/158 (21%)
C2H2 Zn finger 256..276 CDD:275368 7/19 (37%)
zf-H2C2_2 268..293 CDD:290200 10/24 (42%)
C2H2 Zn finger 284..304 CDD:275368 7/19 (37%)
zf-H2C2_2 296..321 CDD:290200 13/24 (54%)
zf-C2H2_2 312..>387 CDD:289522 10/74 (14%)
C2H2 Zn finger 312..332 CDD:275368 8/19 (42%)
C2H2 Zn finger 340..360 CDD:275368 0/19 (0%)
C2H2 Zn finger 369..389 CDD:275368 0/19 (0%)
C2H2 Zn finger 397..417 CDD:275368 0/19 (0%)
zf-H2C2_2 409..434 CDD:290200 7/24 (29%)
C2H2 Zn finger 425..445 CDD:275368 7/19 (37%)
zf-H2C2_2 437..462 CDD:290200 13/24 (54%)
C2H2 Zn finger 453..473 CDD:275368 8/19 (42%)
zf-H2C2_2 465..490 CDD:290200 5/24 (21%)
C2H2 Zn finger 481..501 CDD:275368 4/19 (21%)
Zbtb14NP_001343211.1 BTB_POZ_ZBTB14 18..131 CDD:349513 2/9 (22%)
Nuclear localization signal. /evidence=ECO:0000255 50..66
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 156..194 11/41 (27%)
C2H2 Zn finger 279..299 CDD:275368 7/19 (37%)
SFP1 <303..383 CDD:227516 35/164 (21%)
C2H2 Zn finger 307..327 CDD:275368 7/19 (37%)
zf-H2C2_2 319..344 CDD:404364 13/24 (54%)
C2H2 Zn finger 335..355 CDD:275368 8/19 (42%)
C2H2 Zn finger 363..383 CDD:275368 7/19 (37%)
C2H2 Zn finger 391..407 CDD:275368 7/15 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 405..424 3/18 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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