Protein Alignment CG12299 and let-391

DIOPT Version :10

• Sequence 1: NP_609448.1
• Gene: CG12299 / 34483
• FlyBaseID: FBgn0032295
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_491744.3
• Gene: let-391 / 182953
• WormBaseID: WBGene00006492
• Length: 453
• Species: Caenorhabditis elegans
• Alignment Length: 434
• Identity: 106/434 - (24%)
• Similarity: 164/434 - (37%)
• Gaps: 139/434 - (32%)

  Fly   249 GNQKCFQCTHCEA-----SFPNAGDLSKHVRSHITNKPFQCSICQKTFTHIGSLNTHIRI-HSGE 307
            ||||....|.||.     .:|:.  :.:|:|:|...||::|.||...||....:..|.|: |.|:
 Worm    49 GNQKLPTVTTCEVCGVALKYPSR--IMEHMRTHTGEKPYECDICGMRFTQRTPMINHFRVQHMGD 111

  Fly   308 KPYKCEL-CPKAFTQSSSLMVHMRSHS----------VRKPHQCVQC---DKGFINYSSLLLHQK 358
            .|:.|.. |.|.|..:|....|..||:          ..||.:.:.|   |...::.|:|    .
 Worm   112 LPFLCNFGCGKRFVNNSRRTAHELSHNGLKRAGPARPYLKPVKKIVCPSMDMDILSNSAL----A 172

  Fly   359 THIAP---------------------------TETFICPECEREFKAEAL--------------- 381
            .:|:|                           |:..|.|. |:|.:..|:
 Worm   173 NYISPPTIDSIFQSDPSTSSSSPSQFQSSNQTTKQSIYPS-EKEMEKAAISNARIDDVINTVLAR 236

  Fly   382 ----LDEHMRMHTQE--------------LVYQCAICREAFRASSELVQHMKNHMGEKPFTCSLC 428
                :||.:.:...|              .:.||.||....:..|::..|::.|.|||||.|..|
 Worm   237 VLAPIDEEIPIEEPEKAPQKRAYISNRRATLAQCNICGLMLKHPSKIADHIRTHTGEKPFECGEC 301

  Fly   429 DRSFTQSGSLNIHM-RIHTGEKPFQCK-LCDKCFTQASSLSVH-MKIHAGEKPYPCPI--CGKSY 488
            ..|.:::.||.:|: |:||||:||:|. .|...|...|....| |.:|.|.|.|.|.:  |...:
 Worm   302 GLSLSKASSLKVHIRRMHTGERPFECTWRCGLSFVTDSVRKEHEMTVHTGIKRYTCVVKGCNAVF 366

  Fly   489 SQQAYLNKHIQAHQMASAASASTSPGLLVAKQPHETLVCIVCGSLHADATALASHVHSQHAALLD 553
            :::.||.:|                    .|..|..|.           |.:..||...|....|
 Worm   367 ARRVYLMRH--------------------RKNAHPELF-----------TPIFDHVQVNHEESQD 400

  Fly   554 TM----------KQSGMNTAPGGAIPDVKCSA---EEQQAYVER 584
            ::          .|..|.|..|   .|||..|   ::::.:||:
 Worm   401 SVIVYEDDHEQNNQIIMLTGDG---DDVKILAHFEDDEEEFVEQ 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	245..>501	CDD:227381	88/336 (26%)
		C2H2 Zn finger	256..276	CDD:275368	6/24 (25%)
		C2H2 Zn finger	284..304	CDD:275368	7/20 (35%)
		zf-H2C2_2	296..321	CDD:463886	9/26 (35%)
		C2H2 Zn finger	312..332	CDD:275368	6/20 (30%)
		C2H2 Zn finger	340..360	CDD:275368	4/22 (18%)
		C2H2 Zn finger	369..389	CDD:275368	6/38 (16%)
		C2H2 Zn finger	397..417	CDD:275368	5/19 (26%)
		zf-H2C2_2	409..434	CDD:463886	10/24 (42%)
		C2H2 Zn finger	425..445	CDD:275368	7/20 (35%)
		zf-H2C2_2	437..462	CDD:463886	13/26 (50%)
		C2H2 Zn finger	453..473	CDD:275368	6/21 (29%)
		C2H2 Zn finger	481..501	CDD:275368	5/21 (24%)
let-391	NP_491744.3	C2H2 Zn finger	357..377	CDD:275368	5/39 (13%)
		C2H2 Zn finger	59..79	CDD:275368	5/21 (24%)
		zf-H2C2_2	73..96	CDD:463886	9/22 (41%)
		C2H2 Zn finger	87..108	CDD:275368	7/20 (35%)
		C2H2 Zn finger	116..137	CDD:275368	6/20 (30%)
		C2H2 Zn finger	270..290	CDD:275368	5/19 (26%)
		zf-H2C2_2	286..>302	CDD:463886	8/15 (53%)
		C2H2 Zn finger	298..319	CDD:275368	7/20 (35%)
		C2H2 Zn finger	327..347	CDD:275368	5/19 (26%)