DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12299 and Y37E11B.1

DIOPT Version :9

Sequence 1:	NP_609448.1	Gene:	CG12299 / 34483	FlyBaseID:	FBgn0032295	Length:	736	Species:	Drosophila melanogaster
Sequence 2:	NP_001023441.1	Gene:	Y37E11B.1 / 177118	WormBaseID:	WBGene00021374	Length:	167	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	48/169 - (28%)
Similarity:	69/169 - (40%)	Gaps:	30/169 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 KCELCPKAFTQSSSLMVHMRSH-SVRKPHQCVQCDKGFINYSSLLLHQKTHIAPTETFICPECER 374
            :||:|.:......||..|.|.| ...:..:|..|.|.|.|...|..||..|..|.::.|
Worm    13 QCEICGRILKSDESLRKHERIHDEAERKLECSTCQKRFHNAELLRKHQIVHDIPKKSII------ 71

  Fly   375 EFKAEALLDEHMRMHTQELVYQCAICREAFRASSELVQHMKNHMGEKPFTCSLCDRSFTQSGSLN 439
                                  |.:|.:.:.:.|.|.:|.:.|..:|.|||.:|..||..|....
Worm    72 ----------------------CEVCGKKYSSKSALAKHKRTHETDKRFTCPMCYASFDLSDPFK 114

  Fly   440 IHMRIHTGEKPFQCKLCDKCFTQASSLSVHMKI-HAGEK 477
            ||:|.|...|||.|..|.|.|:..|....|::: |..:|
Worm   115 IHLRKHDNLKPFGCSYCFKQFSSRSVCRRHVQLMHENQK 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	<254..413	CDD:227381	23/102 (23%)
		C2H2 Zn finger	256..276	CDD:275368
		zf-H2C2_2	268..293	CDD:290200
		C2H2 Zn finger	284..304	CDD:275368
		zf-H2C2_2	296..321	CDD:290200	3/9 (33%)
		zf-C2H2_2	312..>387	CDD:289522	19/75 (25%)
		C2H2 Zn finger	312..332	CDD:275368	7/19 (37%)
		C2H2 Zn finger	340..360	CDD:275368	8/19 (42%)
		C2H2 Zn finger	369..389	CDD:275368	0/19 (0%)
		C2H2 Zn finger	397..417	CDD:275368	5/19 (26%)
		zf-H2C2_2	409..434	CDD:290200	10/24 (42%)
		C2H2 Zn finger	425..445	CDD:275368	8/19 (42%)
		zf-H2C2_2	437..462	CDD:290200	11/24 (46%)
		C2H2 Zn finger	453..473	CDD:275368	6/20 (30%)
		zf-H2C2_2	465..490	CDD:290200	3/14 (21%)
		C2H2 Zn finger	481..501	CDD:275368
Y37E11B.1	NP_001023441.1	C2H2 Zn finger	14..34	CDD:275368	7/19 (37%)
		C2H2 Zn finger	43..63	CDD:275368	8/19 (42%)
		C2H2 Zn finger	72..92	CDD:275368	5/19 (26%)
		C2H2 Zn finger	100..120	CDD:275368	8/19 (42%)
		C2H2 Zn finger	128..145	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910