DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12299 and znf1072

DIOPT Version :9

Sequence 1:	NP_609448.1	Gene:	CG12299 / 34483	FlyBaseID:	FBgn0032295	Length:	736	Species:	Drosophila melanogaster
Sequence 2:	XP_017211094.1	Gene:	znf1072 / 108183695	ZFINID:	ZDB-GENE-110913-146	Length:	361	Species:	Danio rerio

Alignment Length:	344	Identity:	109/344 - (31%)
Similarity:	169/344 - (49%)	Gaps:	28/344 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 FQLQMTDPRESTSIFMV-QPTVSVTPLQQ----------LLPPAPTVSPGLGLQSTPIKRRR--- 232
            |.::..|.:|.|.:.:: :.|..:..:::          .....||::.....:..|.|.:.
Zfish    17 FTVKQEDLQEQTDLMVLKEETHQLNVMEEKQQFEKHQVITTDEKPTLTKKTSSRGRPRKSKSMCN 81

  Fly   233 ----------GRRSNIGAPVMDPALNGNQKCFQCTHCEASFPNAGDLSKHVRSHITNKPFQCSIC 287
                      .::||:.   :...::..:|.:.|..|..||........|:..|...:|:.|..|
Zfish    82 YSCTRCRKSFSKKSNLD---IHMRVHTKEKPYTCKQCGKSFGYIQGFENHMSIHTGERPYTCQQC 143

  Fly   288 QKTFTHIGSLNTHIRIHSGEKPYKCELCPKAFTQSSSLMVHMRSHSVRKPHQCVQCDKGFINYSS 352
            .|:|.|.|:...|:|.|:||:.|.|:.|.|:|:::.:|.||||.|:..||:.|.||.|.|....:
Zfish   144 GKSFYHAGNFAAHMRTHTGERKYTCQHCGKSFSKTGNLAVHMRIHTGEKPYSCSQCGKSFKQNVT 208

  Fly   353 LLLHQKTHIAPTETFICPECEREFKAEALLDEHMRMHTQELVYQCAICREAFRASSELVQHMKNH 417
            |.:|.:|| .....|.|.:|.:....:..||.|||:||.|..|.|..|.::|.....|..||.:|
Zfish   209 LKIHMRTH-NEERIFTCTQCGKSISHKHYLDIHMRIHTGEKPYTCTECGKSFPYKGSLKHHMLSH 272

  Fly   418 MGEKPFTCSLCDRSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFTQASSLSVHMKIHAGEKPYPCP 482
            .|||||||:.|.:|||...||..||..|||...|.|..|.|.||:..|:..|||.|:||..:.|.
Zfish   273 TGEKPFTCAQCGKSFTTKTSLMNHMDGHTGIIVFTCDQCGKTFTRKDSMKQHMKTHSGEDSFRCS 337

  Fly   483 ICGKSYSQQAYLNKHIQAH 501
            .|||.:..:..|:.|::.|
Zfish   338 ECGKGFKCKRSLSTHLKLH 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	<254..413	CDD:227381	56/158 (35%)
		C2H2 Zn finger	256..276	CDD:275368	5/19 (26%)
		zf-H2C2_2	268..293	CDD:290200	7/24 (29%)
		C2H2 Zn finger	284..304	CDD:275368	8/19 (42%)
		zf-H2C2_2	296..321	CDD:290200	10/24 (42%)
		zf-C2H2_2	312..>387	CDD:289522	27/74 (36%)
		C2H2 Zn finger	312..332	CDD:275368	9/19 (47%)
		C2H2 Zn finger	340..360	CDD:275368	7/19 (37%)
		C2H2 Zn finger	369..389	CDD:275368	7/19 (37%)
		C2H2 Zn finger	397..417	CDD:275368	6/19 (32%)
		zf-H2C2_2	409..434	CDD:290200	14/24 (58%)
		C2H2 Zn finger	425..445	CDD:275368	9/19 (47%)
		zf-H2C2_2	437..462	CDD:290200	12/24 (50%)
		C2H2 Zn finger	453..473	CDD:275368	9/19 (47%)
		zf-H2C2_2	465..490	CDD:290200	11/24 (46%)
		C2H2 Zn finger	481..501	CDD:275368	6/19 (32%)
znf1072	XP_017211094.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910