DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12299 and znf1040

DIOPT Version :9

Sequence 1:	NP_609448.1	Gene:	CG12299 / 34483	FlyBaseID:	FBgn0032295	Length:	736	Species:	Drosophila melanogaster
Sequence 2:	XP_017211075.1	Gene:	znf1040 / 101884948	ZFINID:	ZDB-GENE-141210-11	Length:	420	Species:	Danio rerio

Alignment Length:	447	Identity:	127/447 - (28%)
Similarity:	196/447 - (43%)	Gaps:	70/447 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 FQLQMTDPRESTSIFMVQPTV----SVTPLQQLLPP-------APTVSPGLGLQSTPIKRRRGRR 235
            |.::..|.:|.|.:.:::...    .:...||...|       .||::........|.|.:.|
Zfish    17 FTVKQEDLQEQTDLMVLKEETHGQNEIDEKQQFEKPQEIMTDEKPTLTKKTSSHGRPRKSKSG-- 79

  Fly   236 SNIGAPVMDPALNGNQKC-FQCTHCEASFPNAGDLSKHVRSHITNKPFQCSICQKTFTHIGSLNT 299
                             | |.|..|..||.....|..|:|.|...:||.|..|.|:|........
Zfish    80 -----------------CNFSCKQCSKSFSQKSKLDVHMRVHTREQPFTCEQCGKSFGQKQGFKA 127

  Fly   300 HIRIHSGEKPYKCELCPKAFTQSSSLMVHMRSHSVRKPHQCVQCDKGFINYSSLLLHQKTHIAPT 364
            |:|||:|::.:.|:.|.|:|..:.:...|||.|:..||..|.||.|.|.:..:|.:|.:.|.. .
Zfish   128 HMRIHTGKRKFTCQQCGKSFYHAGNFAAHMRIHTGEKPFSCKQCGKSFCHKPNLDVHMRVHTG-E 191

  Fly   365 ETFICPECEREFKAEALLDEHMRMHTQELVYQCAICREAFRASSELVQHMKNHMGEKPFTCSLCD 429
            :.:.|.:|.|.|..:...:.|||:||.:....|..|.::|..:..|..||..|.||:||:|.||.
Zfish   192 KPYTCEQCGRSFGQKQSFNTHMRIHTGKRPCTCQQCEKSFYNARSLAAHMITHTGERPFSCILCG 256

  Fly   430 RSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFTQASSLSVHMKIHAGEKPYPCPICGKSYSQQAYL 494
            :||:...:|..|||:||.|||..|:.|.|.|.|...|.:||:||.|||||.|..||||:...:.|
Zfish   257 KSFSLKLTLIAHMRVHTREKPHICEQCGKSFGQKQDLDIHMRIHTGEKPYTCTECGKSFPHISSL 321

  Fly   495 NKHIQAHQMASAASASTSPGLLVAKQPHETLVCIVCGSLHADATALASHVHSQHAALLDTMKQSG 559
            ..||:.|               ..::|   ..|..||......|:|.:|::.....::.|..|.|
Zfish   322 KHHIRTH---------------TGEKP---FTCAQCGKSFTTKTSLKNHMNGHTGTIVFTCDQCG 368

  Fly   560 MN-TAPGGAIPDVKCSAEEQQAYVERVQC--------------VLQQMNHQQQHQQH 601
            .: |........:|..:.|     :|.:|              ...::::.:|:.||
Zfish   369 KSLTRKDSITKHMKIHSRE-----DRFRCSECGKGFKSKRSLNTHMKLHNGEQNPQH 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12299	NP_609448.1	COG5048	<254..413	CDD:227381	51/158 (32%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..293	CDD:290200	10/24 (42%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..321	CDD:290200	9/24 (38%)
		zf-C2H2_2	312..>387	CDD:289522	23/74 (31%)
		C2H2 Zn finger	312..332	CDD:275368	7/19 (37%)
		C2H2 Zn finger	340..360	CDD:275368	7/19 (37%)
		C2H2 Zn finger	369..389	CDD:275368	7/19 (37%)
		C2H2 Zn finger	397..417	CDD:275368	6/19 (32%)
		zf-H2C2_2	409..434	CDD:290200	13/24 (54%)
		C2H2 Zn finger	425..445	CDD:275368	9/19 (47%)
		zf-H2C2_2	437..462	CDD:290200	13/24 (54%)
		C2H2 Zn finger	453..473	CDD:275368	8/19 (42%)
		zf-H2C2_2	465..490	CDD:290200	15/24 (63%)
		C2H2 Zn finger	481..501	CDD:275368	8/19 (42%)
znf1040	XP_017211075.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910