DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha16-5 and Atp6v0c

DIOPT Version :9

Sequence 1:	NP_609447.1	Gene:	Vha16-5 / 34482	FlyBaseID:	FBgn0032294	Length:	193	Species:	Drosophila melanogaster
Sequence 2:	NP_001348460.1	Gene:	Atp6v0c / 11984	MGIID:	88116	Length:	214	Species:	Mus musculus

Alignment Length:	149	Identity:	98/149 - (65%)
Similarity:	117/149 - (78%)	Gaps:	2/149 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PPYSPFYGVMGVVFSSVLTSAGAAYGTAVSGTGIAATAVMRPELVMKSIIPVVMAGIIAIYGLVV 105
            |.||.|:||||...:.|.::.|||||||.|||||||.:||||||:||||||||||||||||||||
Mouse    67 PEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVV 131

  Fly   106 SVLLSGELAPAPKYSLPTGYVHLAAGLSVGFAGLAAGYAVGEVGEVGVRHIALQPRLFIGMILIL 170
            :||::..|...  .:|...::.|.||||||.:|||||:|:|.||:.|||..|.|||||:||||||
Mouse   132 AVLIANSLTDG--ITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILIL 194

  Fly   171 IFAEVLGLYGLIIGIYLYT 189
            ||||||||||||:.:.|.|
Mouse   195 IFAEVLGLYGLIVALILST 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha16-5	NP_609447.1	ATP-synt_C	46..153	CDD:294318	66/106 (62%)
Vha16-5	NP_609447.1	ATP-synt_C	127..187	CDD:278563	43/59 (73%)
Atp6v0c	NP_001348460.1	V_ATP_synt_C	72..177	CDD:130170	66/106 (62%)
Atp6v0c	NP_001348460.1	ATP-synt_C	152..211	CDD:306615	43/58 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834103
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S170
OMA	1	1.010	-	-		QHG53914
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001101
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10263
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X666
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.760