Protein Alignment Nup107 and npp-5

DIOPT Version :9

• Sequence 1: NP_609446.1
• Gene: Nup107 / 34481
• FlyBaseID: FBgn0027868
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: NP_496481.1
• Gene: npp-5 / 174779
• WormBaseID: WBGene00003791
• Length: 813
• Species: Caenorhabditis elegans
• Alignment Length: 847
• Identity: 170/847 - (20%)
• Similarity: 279/847 - (32%)
• Gaps: 255/847 - (30%)

  Fly   131 WRLLHALFYDRILLQTDRQADDEMQDGPTLGGSEKEVIQQLYA------------LNATLREY-- 181
            |..||.::           ::.|||......||......|.||            ..|...||
 Worm    68 WTRLHEIY-----------SEVEMQTRKLPAGSNYSASSQKYANEAVQIASVLSIYTALAHEYDE 121

  Fly   182 --------QLVVD------------WLEACYDRGEQQNPLHAHDR--------------MMAWEN 212
                    :|||:            |.|...  .|||......|:              |||.:.
 Worm   122 TVEVSLLSKLVVEDVEFRRIYALLLWSEKAI--SEQQYEKGLGDKVRKLEGIKSSRINSMMALKR 184

  Fly   213 TLFQLENLQGAAFGKGHKIVTRLDPDAP-VREKRPLHALDEEDNLRLSRAIFELIRAGRVDDGLK 276
            ..|...|....|         .|||||| .:|.:.|..:       .....|:|||:|.......
 Worm   185 PTFGAANAPKDA---------SLDPDAPGTKEDQALEQM-------AMNVFFQLIRSGETSKAAN 233

  Fly   277 LCKHFGQTWRAAILEGWRLHEDPNFEQNVSVLHEKL--PIEGNPRRDIWKRCAWMLADSKNYDEY 339
            |....|.   .||....:||         |:|...|  |:|               |..:|:.||
 Worm   234 LAIDLGM---GAIGAQLQLH---------SMLRNPLDIPLE---------------ASKQNFGEY 271

  Fly   340 SRATAGVFSGHLGSLKTLLHSNWHDLLWAHLKVQIDIRVESEIRGCCLKNYQPM-------PDDY 397
            .|:....:......|......:..|..|..:         |.|||    |.|||       .:..
 Worm   272 KRSRRAKYYQMTQKLIEQSQGSEDDAYWMLI---------SAIRG----NIQPMLKAGKSVIEKV 323

  Fly   398 W--------------NGRMTMEQIFEELNV-AKDASVRDFAQSQLGIIQRHLIL-----DTCGEL 442
            |              .|.||.|.|....|| ....|:.|..:|:....:...||     |...:.
 Worm   324 WAYANSAVLARILAAEGAMTQETISTLFNVPLTSKSILDELRSEADRTKEVYILLRVIDDMLNDD 388

  Fly   443 IQHMVRWVEKDTSQQSPH----QLRFMA-----HIVLFLRQIGRVEQERQAEKIVAAYVEALIAR 498
            |:.:.::..:...:..|:    |:..:|     |:|......| .|.......::....:.|.||
 Worm   389 IEDLYKFANETVGEFVPNDKNCQVNMLALDIFFHLVAVSYASG-FEPNDDGNAVIILGFDDLRAR 452

  Fly   499 ----GEPQLIAYYTASLSNPLQVQLYSRFLEQVEQKRPRELAVDAALQAGLDVEQITRVTVQNIR 559
                ...::.|:|:..|...:::......::.|:....||:..::..|:.:|..:.....::.||
 Worm   453 SGTSSHKKMAAFYSRFLPEDMKLPEIVETMKAVDSDEEREILAESLKQSDIDFGRCACTLIEQIR 517

  Fly   560 LAHQPLGEFGEPQSGEISAIDQRKISALE-------WLIHLPEQRG-ELLWQANAMIRTYLASSK 616
                              ..|:.|:..||       ||:...|:.. ..|.:.|.::|..:.|:.
 Worm   518 ------------------KDDKTKVVTLEEQIDHWHWLLIGGEETALAALEECNRLVRKVMLSTP 564

  Fly   617 VE--CMRQTFRM-----VPADIVQ------QLVSLY--GSVDNIPPREECCLK--EYLCYKAYLS 664
            ::  .:||..|.     ||..:.|      .::||.  |::....|..:..:.  |:...:.|
 Worm   565 IDESVIRQIIRKALHFEVPKLLSQAVENEATVLSLITDGTLFEQKPGSQLAINKIEHAALEFY-- 627

  Fly   665 GVDSFVEWNRLQQNRPKK--------PQTSHAAS------SQDNFT------ERMASERKEQAHR 709
            |:.|||:.|........|        |.|....|      ..||.|      ......|.||..|
 Worm   628 GLCSFVDVNNFMITIALKLGLMFKYTPITDDELSMIGGVKRLDNTTAADWEASLRVRARAEQTLR 692

  Fly   710 SEVVR---WEHKVK----EQAKQTI-----ELLYNVLMFPDKGWLVDPFIAKLPENAVQLSWDHR 762
            .||::   .||..:    :|...|:     .|:.|:.:.|:  :.:.|.....|...      ||
 Worm   693 EEVLKKRAAEHNTRVGMVQQHLDTVLPMLRGLVNNIGVRPE--YFLSPRANGDPMRV------HR 749

  Fly   763 LLQMEKLRSICIPEIALFLNEVMFKSGDFAGCVRLADEISSENRQL-----YKVYTKHKLAELLA 822
             .:::::|::.:|:..:.|.:...:..|   .....|..:|.|..|     :.|:.|...|||..
 Worm   750 -KEIQEIRNLFLPQFFILLAQAAVRLDD---TTNFNDFFTSFNNDLGLDQEWMVFIKAFYAELNL 810

  Fly   823 KI 824
            |:
 Worm   811 KV 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup107	NP_609446.1	Nup84_Nup100	121..828	CDD:309305	170/847 (20%)
npp-5	NP_496481.1	Nup84_Nup100	117..>504	CDD:309305	89/445 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1964
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103478
Panther	1	1.100	-	-	LDO	PTHR13003
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R849
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860