DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EMC3 and emc3

DIOPT Version :9

Sequence 1:	NP_609444.1	Gene:	EMC3 / 34479	FlyBaseID:	FBgn0032292	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_001016907.1	Gene:	emc3 / 549661	XenbaseID:	XB-GENE-942865	Length:	261	Species:	Xenopus tropicalis

Alignment Length:	239	Identity:	153/239 - (64%)
Similarity:	190/239 - (79%)	Gaps:	3/239 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ELLIDPDIRVWVFLPIVLITFLVGIVRHYVSILISTQKKAEITQIQDSQAMIRARLLRENGKYLS 67
            |||:|.:||:||.||||.|||.||::|||||||:.:.||....|:.|||.:||:|:|||||||:|
Frog     5 ELLLDSNIRLWVVLPIVFITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLRENGKYIS 69

  Fly    68 AQSFSMRKNYFNNEETGYFKTQKR---APVAQNSSAMLTDMVKGNFINVLPMVVIGGWINWMFSG 129
            .|||.|||.:|||.|.|:||..||   .|.......|||||:|||..|||||::||||||..|||
Frog    70 KQSFLMRKFFFNNSEDGFFKKTKRKVVPPSPMTDPTMLTDMMKGNVTNVLPMILIGGWINMTFSG 134

  Fly   130 FVTTKVPFPLTLRFKPMLQRGVELASLDAAWVSSASWYFLNVFGLRSIYTLVLGENNHADQTQAQ 194
            |||||||||||||||||||:|:||.||||:|||||||||||||||||||:|:||::|.|||::..
Frog   135 FVTTKVPFPLTLRFKPMLQQGIELLSLDASWVSSASWYFLNVFGLRSIYSLILGQDNAADQSRVM 199

  Fly   195 ADAMTGAAMTMPQDPKAAFKAEWEALEITEYHNALKNIDADMLA 238
            .:.||||||.||.|...|||.||||||:|::..||::::.|:::
Frog   200 QEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALEDLEEDLMS 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EMC3	NP_609444.1	DUF106	3..185	CDD:396507	127/184 (69%)
emc3	NP_001016907.1	DUF106	5..190	CDD:396507	127/184 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	265	1.000	Domainoid score	I1859
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2486
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1482782at2759
OrthoFinder	1	1.000	-	-		FOG0003058
OrthoInspector	1	1.000	-	-		otm48793
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1973
SonicParanoid	1	1.000	-	-		X2419
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090