DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17118 and CFAP20

DIOPT Version :9

Sequence 1:	NP_723611.1	Gene:	CG17118 / 34478	FlyBaseID:	FBgn0032291	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_037374.1	Gene:	CFAP20 / 29105	HGNCID:	29523	Length:	193	Species:	Homo sapiens

Alignment Length:	183	Identity:	113/183 - (61%)
Similarity:	147/183 - (80%)	Gaps:	0/183 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYRAAYQKGFLTVLYSVGSSPLNNWSSYTKNGYIKRIYDEDIKSLVLEIMGSNVSTTFIHCPSEC 65
            |::..:|.|||::|||:||.||..|....:||:||||.|.||:||||||.|:|||||:|.||::.
Human     1 MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADP 65

  Fly    66 KEQLGIKLPFLVLLIKNMHKYFCFEVKIQDDQRFMRRFRVSNFQSKTSVKPFCTAMPMGMSPGWN 130
            |:.|||||||||::|||:.|||.|||::.||:...||||.||:||.|.||||...|||.:..|||
Human    66 KKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWN 130

  Fly   131 QIQFNLADFTRRAYGSNYLETVSLQLHANVRIRRIYFADKLYTEAELPNDYRL 183
            ||||||.||||||||:||:||:.:|:|||.||||:||:|:||:|.|||.:::|
Human   131 QIQFNLLDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKL 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17118	NP_723611.1	DUF667	1..184	CDD:398611	113/183 (62%)
CG17118	NP_723611.1	PHA03247	<193..279	CDD:223021
CFAP20	NP_037374.1	DUF667	1..185	CDD:398611	113/183 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156665
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3213
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1213295at2759
OrthoFinder	1	1.000	-	-		FOG0005006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12458
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.810