Protein Alignment CG17118 and WDR90

DIOPT Version :10

• Sequence 1: NP_723611.1
• Gene: CG17118 / 34478
• FlyBaseID: FBgn0032291
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: XP_047289678.1
• Gene: WDR90 / 197335
• HGNCID: 26960
• Length: 1847
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 70/311 - (22%)
• Similarity: 122/311 - (39%)
• Gaps: 64/311 - (20%)

  Fly     5 AYQKGFLTVLYSVGSSPLNNWSSYTKNGYIKRIYDEDIKSLVLEIMGSNVSTTFIHCPSECKEQL 69
            |:|..||.|....   .::.|....|.|.:..:.|:.:|..|..|.||..:..:|..|....:.|
Human    13 AWQHPFLNVFRHF---RVDEWKRSAKQGDVAVVTDKTLKGAVYRIRGSVSAANYIQLPKSSTQSL 74

  Fly    70 GIKLPFLVLLIKNM-HKYFCFEVKIQDDQRFMRRFRVSN----FQSKTSVKPFCTAMP------- 122
            |:...:|.:|.:.: .|:|...:.:......:.|...||    |:|..:...|...:.
Human    75 GLTGRYLYVLFRPLPSKHFVIHLDVSSKDNQVIRVSFSNLFKEFKSTATWLQFPLVLEARTPQRD 139

  Fly   123 -MGMSPG---WNQIQFNLAD----FTRRAYGSNYLETVSLQLHANVRIRRIYFADKLYTEAELPN 179
             :|::|.   |..:|.:|.|    :..|.||  :|:  |::|.|::.:|.:|.:|..:..|
Human   140 LVGLAPSGARWTCLQLDLQDVLLVYLNRCYG--HLK--SIRLCASLLVRNLYTSDLCFEPA---- 196

  Fly   180 DYRLMGKPKDLKKPEKQFKVQATARPPSPLNTGRGEPGPS----KDTDAEATGPATDPMSEPEPA 240
               :.|             .|....|.:|:......|.|.    .|.......| ::.:..|...
Human   197 ---ISG-------------AQWAKLPVTPMPREMAFPVPKGESWHDRYIHVRFP-SESLKVPSKP 244

  Fly   241 LQKSPSPPV-------PQKVPSPAASAPP-----EPATEEPAPQTEATEEA 279
            ::||.|||.       ||.:|.|.||:.|     .|..:.|:|..::...|
Human   245 IEKSCSPPEAVLLGPGPQPLPCPVASSKPVRFSVSPVVQTPSPTAQSGRAA 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17118	NP_723611.1	CFA20_dom	1..184	CDD:461521	45/198 (23%)
		PHA03247	<193..279	CDD:223021	23/101 (23%)
WDR90	XP_047289678.1	CFA20_dom	13..190	CDD:461521	43/183 (23%)
		WD40	400..777	CDD:441893
		WD40 repeat	422..460	CDD:293791
		WD40 repeat	466..514	CDD:293791
		WD40 repeat	520..558	CDD:293791
		WD40 repeat	563..615	CDD:293791
		WD40	603..1013	CDD:441893
		WD40 repeat	633..664	CDD:293791
		WD40 repeat	671..706	CDD:293791
		WD40 repeat	713..749	CDD:293791
		WD40 repeat	829..872	CDD:293791
		WD40 repeat	898..939	CDD:293791
		WD40 repeat	946..983	CDD:293791
		PRK12323	<993..>1138	CDD:481241
		WD40	1235..1650	CDD:441893
		WD40 repeat	1259..1300	CDD:293791
		WD40 repeat	1306..1344	CDD:293791
		WD40 repeat	1352..1396	CDD:293791
		WD40 repeat	1401..1435	CDD:293791
		WD40 repeat	1491..1532	CDD:293791
		WD40	1526..1844	CDD:475233
		WD40 repeat	1537..1573	CDD:293791
		WD40 repeat	1580..1621	CDD:293791
		WD40 repeat	1627..1663	CDD:293791