Protein Alignment CG6443 and RTF2

DIOPT Version :10

• Sequence 1: NP_609443.1
• Gene: CG6443 / 34477
• FlyBaseID: FBgn0032290
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_001269964.1
• Gene: RTF2 / 51507
• HGNCID: 15890
• Length: 336
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 126/346 - (36%)
• Similarity: 188/346 - (54%)
• Gaps: 61/346 - (17%)

  Fly     1 MGCDGGTIPRRDELVRVKQKPEQ------------------------------KDKDAEREFRWR 35
            |||||||||:|.|||:..:|.|:                              .|||||...:|.
Human     1 MGCDGGTIPKRHELVKGPKKVEKIWHLKNGKEWCSLHSEGKNKNGKEWDMEYDVDKDAELVAQWN 65

  Fly    36 HCTLTQQSLQEPIAMCGMGRLYSKQSVIERLLEK---EPMPETAAHVKSMKDIRQLNPTPNPAF- 96
            :|||:|:.|:.||..|.:||||:|.:|||.||:|   :.:.:.|:|:||:|::.:|..:.|||:
Human    66 YCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKAASHIKSIKNVTELKLSDNPAWE 130

  Fly    97 -----TEEDKTEGLLDTRHSPYICKLIGLEMSGKFRFVALWSCGCVLSERALKQIKGSVASTCPL 156
                 |:.||.:   |.:.:.:||.::||||:|:.||..|..||||.||||||:||   |..|..
Human   131 GDKGNTKGDKHD---DLQRARFICPVVGLEMNGRHRFCFLRCCGCVFSERALKEIK---AEVCHT 189

  Fly   157 CQAAYSVEDVVVLNGNEEDMELMRVKMEMRAAKRKSSKKDKKSAKKVEVKAEPAEEQEPVASTSK 221
            |.||:..:||::|||.:||:::::.:||.|..:.|..||.||......|......|:.|..|..|
Human   190 CGAAFQEDDVIMLNGTKEDVDVLKTRMEERRLRAKLEKKTKKPKAAESVSKPDVSEEAPGPSKVK 254

  Fly   222 AAAAEKPTTSTKTKAVAPVKRLGAVN------AMQDP--ELKRLKSDFSVAKDPKASDVYKSLFT 278
            ....|:.:..::.|......:..|:|      |.:.|  ..||     |:| |.:.|:.||||||
Human   255 TGKPEEASLDSREKKTNLAPKSTAMNESSSGKAGKPPCGATKR-----SIA-DSEESEAYKSLFT 313

  Fly   279 SHKTEK--DQERAHWVTYNPF 297
            :|.:.|  .:|.|||||:..:
Human   314 THSSAKRSKEESAHWVTHTSY 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6443	NP_609443.1	Rtf2	1..284	CDD:398360	119/329 (36%)
RTF2	NP_001269964.1	Rtf2	1..319	CDD:398360	119/329 (36%)