Protein Alignment CG6431 and LIPG

DIOPT Version :10

• Sequence 1: NP_001188790.1
• Gene: CG6431 / 34476
• FlyBaseID: FBgn0032289
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: NP_006024.1
• Gene: LIPG / 9388
• HGNCID: 6623
• Length: 500
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 93/321 - (28%)
• Similarity: 137/321 - (42%)
• Gaps: 65/321 - (20%)

  Fly    54 ETCPKRFIDYQLFTSNGP-RRGTPLNVKNPITLYKGGFSKHRETVFIIHGFNGTAI-DIHLQFLR 116
            :|..|..:.:.|.||..| ..|..|:|.:...|....|:...:|.|||||:..:.| :..|..|.
Human    42 QTEVKPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLV 106

  Fly   117 DAYLSR--DFNVITVDWRPLTRYPCYLHSLINTRLTAQCTAQIYAFLTHYGAVRER-------IT 172
            .|..:|  |.||:.|||.||. :..|..::.|||:.....|::..:|      :|:       :.
Human   107 SALHTREKDANVVVVDWLPLA-HQLYTDAVNNTRVVGHSIARMLDWL------QEKDDFSLGNVH 164

  Fly   173 CVGHSLGAHICGMISNHLTRKQYRIIGLDPARPLIERMKSNKFRLSIDDANVIQVLHT---NAGF 234
            .:|:|||||:.|...|.:.....||.|||||.|:.|....:| |||.|||:.:.||||   :.|.
Human   165 LIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHK-RLSPDDADFVDVLHTYTRSFGL 228

  Fly   235 -LGQEDNSGHLNYCVNGGRIQPFCKGNPIRKS----------RCSH------FL---------SI 273
             :|.:...||::...|||..||.|..|.:..|          :|.|      |:         |.
Human   229 SIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSF 293

  Fly   274 CYLATATFKHNKFMGVPCPNGCLNLSGSKRLPVSGKVN-----------PFEFASLIREYH 323
            .:..|.:.:..|.:.:.|.....|..|.....:..|.|           ||      |.||
Human   294 AFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPF------RVYH 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6431	NP_001188790.1	alpha/beta hydrolases	63..293	CDD:473884	82/269 (30%)
LIPG	NP_006024.1	lipo_lipase	50..485	CDD:132274	91/313 (29%)