DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6431 and lipca

DIOPT Version :9

Sequence 1:	NP_001188790.1	Gene:	CG6431 / 34476	FlyBaseID:	FBgn0032289	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	281	Identity:	77/281 - (27%)
Similarity:	126/281 - (44%)	Gaps:	56/281 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LTSLIALLLSLLSLNPITNASKYHREALQFLLRNGN-FDLNPLNCHILLWETCPKRFIDYQLFTS 68
            :.:||.::|..|.::.:|:.:.:          .|| .|..|.....:.:|  ||..  ::::|.
Zfish     1 MKTLIKIVLCFLMISQLTDGATF----------QGNRADTEPEARMKMRYE--PKSV--FRVYTD 51

  Fly    69 NGPRRGT-PLNVKNPITLYKGGFSKHRETVFIIHGFNGTAIDIHLQFLRDAYLSR---------- 122
            ......| .|.:..|.||...||:.......||||::       :..:.:.::||
Zfish    52 GEYTEDTCALELFQPHTLDACGFNSSLPLAIIIHGWS-------VDGMMEKWISRLASALKSSEG 109

  Fly   123 DFNVITVDWRPLT--RYPCYLHSLINTRLTAQCTAQIYAFLTHY-----GAVRERITCVGHSLGA 180
            :.||:..||..|.  .||.   :..|||:..|..|.:.::|..:     |    ::..:|:||||
Zfish   110 NINVLIADWLTLAHQHYPI---AAQNTRIVGQDIAHLLSWLEDFKQFPLG----KVHLIGYSLGA 167

  Fly   181 HICGMISNHLT---RKQYRIIGLDPARPLIERMKSNKFRLSIDDANVIQVLHT----NAGF-LGQ 237
            ||.|...::|.   |...||.|||||.|:.|.| |:..|||.:||..:..:||    ..|. :|.
Zfish   168 HISGFAGSNLAMSGRTLGRITGLDPAGPMFEGM-SHTDRLSPEDAKFVDAIHTFTLQRMGLSVGI 231

  Fly   238 EDNSGHLNYCVNGGRIQPFCK 258
            :....|.::..|||..||.|:
Zfish   232 KQPVAHFDFYPNGGSFQPGCQ 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6431	NP_001188790.1	Abhydrolase	63..293	CDD:304388	65/222 (29%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	65/226 (29%)
		Pancreat_lipase_like	54..344	CDD:238363	64/214 (30%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910