DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6431 and PNLIPRP3

DIOPT Version :9

Sequence 1:	NP_001188790.1	Gene:	CG6431 / 34476	FlyBaseID:	FBgn0032289	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_001011709.2	Gene:	PNLIPRP3 / 119548	HGNCID:	23492	Length:	467	Species:	Homo sapiens

Alignment Length:	322	Identity:	80/322 - (24%)
Similarity:	124/322 - (38%)	Gaps:	73/322 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LLW--ETCPKRFIDYQLFTSNGPRRGTPLNVKNPITLYKGGFSKHRETVFIIHGFNGTA------ 107
            |.|  |....||:   |:|.:.|.....::..|..|:....|...:.|...|.|:....
Human    45 LPWSPEKINTRFL---LYTIHNPNAYQEISAVNSSTIQASYFGTDKITRINIAGWKTDGKWQRDM 106

  Fly   108 IDIHLQFLRDAYLSRDFNVITVDWRPLTRYPCYLHSLINTRLT-AQCTAQIYAFLTHYGAVRERI 171
            .::.||.       .|.|.|.:||...:|.  |:|::.|.|:. |:....|...:..:.....::
Human   107 CNVLLQL-------EDINCINLDWINGSRE--YIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKV 162

  Fly   172 TCVGHSLGAHICGMISNHLTRKQYRIIGLDPARPLIERMKSNKFRLSIDDANVIQVLHTNAGFL- 235
            ..:|||||||:.|...:.:.... ||.|||||.|.... ...:.||...|||.:.|:||||..:
Human   163 HLIGHSLGAHLAGEAGSRIPGLG-RITGLDPAGPFFHN-TPKEVRLDPSDANFVDVIHTNAARIL 225

  Fly   236 -----GQEDNSGHLNYCVNGGRIQPFCKG----------NPIRKSR-----CSHFLSICYLATAT 280
                 |..|..|||::..|||:..|.|:.          |..:|..     |:|..|..:.|.:.
Human   226 FELGVGTIDACGHLDFYPNGGKHMPGCEDLITPLLKFNFNAYKKEMASFFDCNHARSYQFYAESI 290

  Fly   281 FKHNKFMGVPC---------------PNGC--------------LNLSGSKRLPVSGKVNPF 313
            ...:.|:..||               ..||              :..:||.....:|.::||
Human   291 LNPDAFIAYPCRSYTSFKAGNCFFCSKEGCPTMGHFADRFHFKNMKTNGSHYFLNTGSLSPF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6431	NP_001188790.1	Abhydrolase	63..293	CDD:304388	68/272 (25%)
PNLIPRP3	NP_001011709.2	Lipase	18..352	CDD:278576	78/320 (24%)
		Pancreat_lipase_like	52..348	CDD:238363	74/309 (24%)
		PLAT_PL	355..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910