DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6415 and amt

DIOPT Version :9

Sequence 1:	NP_609441.1	Gene:	CG6415 / 34474	FlyBaseID:	FBgn0032287	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001006021.1	Gene:	amt / 450000	ZFINID:	ZDB-GENE-041010-114	Length:	409	Species:	Danio rerio

Alignment Length:	400	Identity:	201/400 - (50%)
Similarity:	259/400 - (64%)	Gaps:	23/400 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RHASSAAGEG---------------QRTALYDFHVQKGGKIVNFGGYALPVQYSDQSIIASHLHT 65
            |.::.|.|.|               ::|.|||||...|||:|.|.|:::||||.| |.|.||:||
Zfish    16 RESTRAVGLGATGRQDRQASTEVTLRKTPLYDFHRAHGGKMVEFAGWSMPVQYKD-SHITSHMHT 79

  Fly    66 RQVGSIFDVSHMLQSRIFGKDAAACLESVCTADILGTPEGSGSLTVFTNEAGGILDDLIVNKVSE 130
            ||..||||||||||::::|||....:||:...||....:..|:|::|||..|||:|||||.|..:
Zfish    80 RQHCSIFDVSHMLQTKVYGKDRVKFIESLIVGDIAELKDNQGTLSLFTNSKGGIMDDLIVTKTDQ 144

  Fly   131 KELYVVSNAAMKEQDMGIMKTAVDNFKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTGKA 195
            ..|||||||...::|...|:..:..|||.|.||.:||:   ::||:|:|||.:|:.|.|.:..
Zfish   145 DYLYVVSNAGCADKDSAHMQARLQEFKSAGHDVDLEFM---EESLIALQGPSMARVLQKGVGD-- 204

  Fly   196 SLDQLYFMSSFVTTLAGIPNVRITRCGYTGEDGVEISVASSQAQKLTESLLESGVLKLAGLGARD 260
            .|.:|.||:|.:|.:.||...|:|||||||||||||||.|.....|||.||....:|||||||||
Zfish   205 DLKKLTFMTSVLTPVFGIQGCRVTRCGYTGEDGVEISVPSKDVVLLTEKLLADSEVKLAGLGARD 269

  Fly   261 SLRLEAGLCLYGSDIDSKTTPVEAALAWLVTKRRRTTRDFPGADVILGQLKEGVSRRRVGLQMLG 325
            ||||||||||||:|||..||||||.|.|.:.||||..|||||||:|:.|:|....|:||||  :.
Zfish   270 SLRLEAGLCLYGNDIDETTTPVEATLVWTIGKRRRQARDFPGADIIVPQIKAKTPRKRVGL--IS 332

  Fly   326 TKPPPARSGVAIFSQGQQVGQVTSGCPSPSAGRNIAMGYVAENLKAPGTKVEFKVRDKLYEAEVT 390
            |.||..:....:.|.|:.:|:||||||||...:|:|||||.......||.::.:||.|...|.|:
Zfish   333 TGPPVRQHTPILSSDGRVIGEVTSGCPSPCLKQNVAMGYVETAFSKAGTSIQVEVRKKAVPAVVS 397

  Fly   391 KMPFVKANYY 400
            |||||...||
Zfish   398 KMPFVPTKYY 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	PLN02319	3..403	CDD:177953	200/399 (50%)
		GCV_T	31..288	CDD:279857	141/256 (55%)
		GCV_T_C	298..392	CDD:285832	42/93 (45%)
amt	NP_001006021.1	PLN02319	2..407	CDD:177953	199/398 (50%)
		GCV_T	46..298	CDD:279857	141/257 (55%)
		GCV_T_C	307..399	CDD:285832	42/93 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584101
Domainoid	1	1.000	274	1.000	Domainoid score	I1748
eggNOG	1	0.900	-	-		E1_COG0404
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H409
Inparanoid	1	1.050	378	1.000	Inparanoid score	I2041
OMA	1	1.010	-	-		QHG53675
OrthoDB	1	1.010	-	-		D306101at33208
OrthoFinder	1	1.000	-	-		FOG0004170
OrthoInspector	1	1.000	-	-		oto38627
orthoMCL	1	0.900	-	-		OOG6_101103
Panther	1	1.100	-	-	LDO	PTHR43757
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R483
SonicParanoid	1	1.000	-	-		X2922
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800