DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6415 and Sardh

DIOPT Version :9

Sequence 1:	NP_609441.1	Gene:	CG6415 / 34474	FlyBaseID:	FBgn0032287	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_611263.1	Gene:	Sardh / 37026	FlyBaseID:	FBgn0034276	Length:	894	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	107/428 - (25%)
Similarity:	181/428 - (42%)	Gaps:	76/428 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RHASSAAGEGQRTALYDFHVQKGGKIVNFGGYALPVQYSDQSIIASH-LHTRQVGSIFDVSHMLQ 79
            ||..|   |.:|....|.|            |:...:|.|  :|.|. |..|....:|::|:..:
  Fly   501 RHKDS---EYERVLDGDLH------------YSRFSEYHD--LIGSEALACRNNAVVFNMSYFAK 548

  Fly    80 SRIFGKDAAACLESVCTADILGTPEGSGSLTVFT---NEAGGILDDLIVN------------KVS 129
            ..:.|..|....:.:.:|:....|    |.||:|   |:|||:..|:.::            |::
  Fly   549 LLLDGPQAQEAADWLFSANTNRDP----SKTVYTCALNDAGGVEADVTISRLAPGSGEVYNPKIN 609

  Fly   130 EKELYVVSNAAMKEQDMGIMKTAVDNFKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTGK 194
            .:..|:|:..|.......::...:   :.:|.:.|::.|| |:..::::|||...|.|..|:...
  Fly   610 GQGFYIVAGGASAFYTYSVLLAEI---RRKGFNASLKDLT-AELGVISIQGPNSRKILQPLIDCD 670

  Fly   195 ASLDQLYFMSSFVTTLA--GIPNVRITRCGYTGEDGVEISVASSQAQKLTESLLESGV---LKLA 254
            .| |:....:|  |.||  |...:|:.|..:.||.|.|:.|.......:..||:::|.   |:.|
  Fly   671 LS-DEHVAPNS--TRLAKFGDVGLRLLRVSFVGELGYELHVPKKDCAAVYRSLMKAGAGEDLRNA 732

  Fly   255 GLGARDSLRLEAGLCLYGSDIDSKTTPVEAALAWLVTKRRRTTRDFPGADVILGQLKEGVSRRRV 319
            |..:..||..|.|..|:..|:....||:||.|.:..   |:|..|:.|...|..|..||:.:|.|
  Fly   733 GYRSLYSLSSEKGYHLWSFDLRPDDTPLEAGLGFTC---RKTGADYRGKAAIENQRAEGLKKRLV 794

  Fly   320 GLQMLGTKPPPARSGVAIFSQGQQVGQVTSGCPSPSAGRNIAMGYVAENLKAPGTKV-------- 376
            .|.:....|.....||  :..|:.||.:.....:.:.|:::...||:.    |..|:
  Fly   795 YLTLRDQVPIWGLEGV--YRNGEPVGILRRAEYAYTLGKSLGQTYVSR----PDGKIIDADYIRN 853

  Fly   377 ---EFKVRDKLYEAEV-TKMPF------VKANYYNRPK 404
               |..:..|.|.|:. .:.||      |..||.:..|
  Fly   854 GEYEVDILGKKYRADCHLRSPFDPTGQRVLGNYASESK 891

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	PLN02319	3..403	CDD:177953	106/425 (25%)
		GCV_T	31..288	CDD:279857	70/277 (25%)
		GCV_T_C	298..392	CDD:285832	24/105 (23%)
Sardh	NP_611263.1	DadA	33..412	CDD:223737
		NADB_Rossmann	37..>76	CDD:304358
		nuc_hydro	203..>281	CDD:294156
		FAO_M	398..449	CDD:292961
		GcvT	446..884	CDD:223481	104/419 (25%)
		GCV_T	456..767	CDD:279857	75/293 (26%)
		GCV_T_C	774..867	CDD:285832	23/98 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456406
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0404
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740