DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6415 and Pdpr

DIOPT Version :9

Sequence 1:	NP_609441.1	Gene:	CG6415 / 34474	FlyBaseID:	FBgn0032287	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_938050.1	Gene:	Pdpr / 319518	MGIID:	2442188	Length:	878	Species:	Mus musculus

Alignment Length:	429	Identity:	95/429 - (22%)
Similarity:	170/429 - (39%)	Gaps:	77/429 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GEGQRTA-LYDFHVQKGGKIVNFGGYALPVQYSDQSIIASHLHTRQVGSIFDVSHMLQSRIFGK- 85
            |...||: |||....:|.:.:...|:..|..:              |....|:..:.||:.|.|
Mouse   453 GRQLRTSPLYDRLDAQGARWMEKHGFERPKYF--------------VPPNKDLLALEQSKTFYKP 503

  Fly    86 --------DAAACLESVCTADI--------------------------LGTPEGSGSLTVFTNEA 116
                    :...|.|:||..|:                          |..|.|....|...||.
Mouse   504 DWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDEALESLQYLFCNDLDVPVGHIVHTGMLNEY 568

  Fly   117 GGILDDLIVNKVSEKELYVVSNAAMKEQDMGIMKTA-VDNFKSQGKDVSIEFLTPADQSLVAVQG 180
            ||..:|..:.:::::..:::|     ..|..:...| ::.:..:..::.:|.:|....:|..: |
Mouse   569 GGYENDCSIARLTKRSFFMIS-----PTDQQVHCWAWLNKYLPKDSNLLLEDVTWKYTALNLI-G 627

  Fly   181 PQVAKELSKLLTGKASLDQLYFMSSFVTTLA-GIPN-VRITRCGYTGEDGVEISVASSQAQKLTE 243
            |:....||:|.....:.|  :|.:.|...:: |..| :|:....:|||.|..:.:....|..:..
Mouse   628 PRAVDVLSELSYAPMTPD--HFPTLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYN 690

  Fly   244 SLLESGV---LKLAGLGARDSLRLEAGLCLYGSDIDSKTTPVEAALAWLVTKRRRTTRDFPGADV 305
            .::..|.   ::.||..|..|||:|.....:|.|:::.|||:|......|...:..  ||.|.|.
Mouse   691 EVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGI--DFIGRDA 753

  Fly   306 ILGQLKEGVSRRRVGLQMLGTKPPPARS----GVAIFSQGQQVGQVTSGCPSPSAGRNIAMGYVA 366
            :|.|.:.|| .:|:.:.:|.........    |..|:..|:..|:.||...|.:..|::.:|||
Mouse   754 LLQQKQTGV-YKRLAMFILDDHDTDLDLWPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYV- 816

  Fly   367 ENLKAPGTKVEFKVRDKL----YEAEVTKMPF-VKANYY 400
            .|......:.:....|.:    ||.::....| .||..|
Mouse   817 HNFSEDSGEEQVVTTDFINRGEYEIDIAGHRFQAKAKLY 855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	PLN02319	3..403	CDD:177953	95/429 (22%)
		GCV_T	31..288	CDD:279857	61/297 (21%)
		GCV_T_C	298..392	CDD:285832	25/101 (25%)
Pdpr	NP_938050.1	DadA	38..425	CDD:223737
Pdpr	NP_938050.1	GcvT	452..867	CDD:223481	95/429 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810