DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6415 and Amt

DIOPT Version :9

Sequence 1:	NP_609441.1	Gene:	CG6415 / 34474	FlyBaseID:	FBgn0032287	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_038937253.1	Gene:	Amt / 306586	RGDID:	1359408	Length:	408	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	196/375 - (52%)
Similarity:	257/375 - (68%)	Gaps:	8/375 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QRTALYDFHVQKGGKIVNFGGYALPVQYSDQSIIASHLHTRQVGSIFDVSHMLQSRIFGKDAAAC 90
            :||.|||||:..|||:|.|.|::|||||.| |.:.||||||:..|:||||||||::|||.|....
  Rat    39 RRTPLYDFHLAHGGKMVAFAGWSLPVQYRD-SHVDSHLHTRRHCSLFDVSHMLQTKIFGCDRVRL 102

  Fly    91 LESVCTADILGTPEGSGSLTVFTNEAGGILDDLIVNKVSEKELYVVSNAAMKEQDMGIMKTAVDN 155
            :|::...||.......|:|::||||||||||||||...||..|||||||..:::|:.:|:..|..
  Rat   103 MENIVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCRDKDLALMQDKVKE 167

  Fly   156 FKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTGKASLDQLYFMSSFVTTLAGIPNVRITR 220
            |:::|.||.:|.:   |.:|:|:|||..|:.|...:|.  .:.:|.||:|.|..:.|:...|:||
  Rat   168 FQNRGLDVGLEVV---DNALLALQGPTAAQVLQAGVTD--DMRKLPFMTSAVMEVFGVSGCRVTR 227

  Fly   221 CGYTGEDGVEISVASSQAQKLTESLLESGVLKLAGLGARDSLRLEAGLCLYGSDIDSKTTPVEAA 285
            |||||||||||||.::.|..|..:||::..:|||||.|||||||||||||||:|||..|||||.:
  Rat   228 CGYTGEDGVEISVPAAGAVHLATALLKNPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGS 292

  Fly   286 LAWLVTKRRRTTRDFPGADVILGQLKEGVSRRRVGLQMLGTKPPPARSGVAIFSQGQQVGQVTSG 350
            |:|.:.||||...|||||.:|:.|||..|.||||||...|. |..|.|.: :.::|..:|.||||
  Rat   293 LSWTLGKRRRVAMDFPGAKIIIPQLKGEVQRRRVGLICEGA-PMRAHSPI-LNTEGAVIGTVTSG 355

  Fly   351 CPSPSAGRNIAMGYVAENLKAPGTKVEFKVRDKLYEAEVTKMPFVKANYY 400
            |||||..:|:||||||.....|||::..:||.|.....|:|||||...||
  Rat   356 CPSPSLKKNVAMGYVAFKYSRPGTQLLVEVRRKQQMTVVSKMPFVPTKYY 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	PLN02319	3..403	CDD:177953	196/375 (52%)
		GCV_T	31..288	CDD:279857	136/256 (53%)
		GCV_T_C	298..392	CDD:285832	45/93 (48%)
Amt	XP_038937253.1	GCV_T	16..405	CDD:423040	194/373 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2733
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H409
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2535
OMA	1	1.010	-	-		QHG53675
OrthoDB	1	1.010	-	-		D306101at33208
OrthoFinder	1	1.000	-	-		FOG0004170
OrthoInspector	1	1.000	-	-		oto98616
orthoMCL	1	0.900	-	-		OOG6_101103
Panther	1	1.100	-	-	LDO	PTHR43757
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2922
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980