Protein Alignment CG6415 and DMGDH

DIOPT Version :10

• Sequence 1: NP_609441.1
• Gene: CG6415 / 34474
• FlyBaseID: FBgn0032287
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_037523.2
• Gene: DMGDH / 29958
• HGNCID: 24475
• Length: 866
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 100/377 - (26%)
• Similarity: 161/377 - (42%)
• Gaps: 62/377 - (16%)

  Fly    26 QRTALYDFHVQKGGKIVNFGGYALPVQYSDQSIIASHLHTRQVGSI--FDVSHMLQSRIFGKDAA 88
            ||.|:.|        :..||.:.:..|  |...:..||....:..:  .::||||
Human   527 QRVAVTD--------LSPFGKFNIKGQ--DSIRLLDHLFANVIPKVGFTNISHML---------- 571

  Fly    89 ACLESVCTADILGTPEGSGSLTVFTNEAGGILDDLIVNKVSEKELYVVSNAAMKEQDM-GIMKTA 152
                         ||:|.            :..:|.|:..|..|..:::.:..:..|: .|.:.|
Human   572 -------------TPKGR------------VYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEA 611

  Fly   153 VDNFKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTGKASLDQLYFMSSFVTTLAGIPNVR 217
            |..    |.||.|:.:|. :..::.|.|||..|.|.||.:...|.|...|:.:....::.|| |.
Human   612 VKG----GYDVEIKNITD-ELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIP-VT 670

  Fly   218 ITRCGYTGEDGVEISVASSQAQKLTESLLESGV---LKLAGLGARDSLRLEAGLCLYGSDIDSKT 279
            ..|..||||.|.|:......:..|.::::.:|.   :...|..|.::||||.....:|.:::..|
Human   671 AIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDT 735

  Fly   280 TPVEAALAWLVTKRRRTTRDFPGADVILGQLK-EGVSRRRVGLQMLGTKPPPARSGVAIFSQGQQ 343
            .|:||.|.:.|  :.....||.|... |.|:| :|:.||.|.| .|.|.........:|:..|:.
Human   736 NPLEAGLEYFV--KLNKPADFIGKQA-LKQIKAKGLKRRLVCL-TLATDDVDPEGNESIWYNGKV 796

  Fly   344 VGQVTSGCPSPSAGRNIAMGYVAENLKAPGTKVEFKVRDKLYEAEVTKMPFV 395
            ||..|||..|.|..:::|..||...|...|.:||.::..|.|.|.:.:.|.|
Human   797 VGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLV 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	gcvT	3..403	CDD:476863	100/377 (27%)
DMGDH	NP_037523.2	DadA	49..431	CDD:440429
		FAO_M	417..472	CDD:465100
		GcvT	465..857	CDD:440173	100/377 (27%)