DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6415 and gcv1

DIOPT Version :9

Sequence 1:	NP_609441.1	Gene:	CG6415 / 34474	FlyBaseID:	FBgn0032287	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_594015.1	Gene:	gcv1 / 2543195	PomBaseID:	SPAC31G5.14	Length:	387	Species:	Schizosaccharomyces pombe

Alignment Length:	393	Identity:	173/393 - (44%)
Similarity:	243/393 - (61%)	Gaps:	13/393 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AALGGLRHASSAAGEG--QRTALYDFHVQKGGKIVNFGGYALPVQYSDQSIIASHLHTRQVGSIF 72
            |||..|:..||.|...  :||.|||.|:::|..||.|.|:::||||..|:|.|||..||:...:|
pombe     5 AALSILKRQSSTAASSSLKRTPLYDLHLKEGATIVPFAGFSMPVQYKGQTISASHKWTREHSGLF 69

  Fly    73 DVSHMLQSRIFGKDAAACLESVCTADILGTPEGSGSLTVFTNEAGGILDDLIVNKVSEKELYVVS 137
            |||||:|..:.|::|.|.|||:..:.:........:|:.||||.|||:||.|::|..|...|:|:
pombe    70 DVSHMVQWFVRGENATAYLESITPSSLKELKPFHSTLSAFTNETGGIIDDTIISKQDENTYYIVT 134

  Fly   138 NAAMKEQDMGIMKTAVDNFKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTGKASLDQLYF 202
            |||..|:|...:|..::|:|      .:|......::|:|:|||:.|..:.||:. ......|.|
pombe   135 NAACSEKDEANLKKHIENWK------GVELERVQGRALIAIQGPETASVVQKLIP-NVDFSVLKF 192

  Fly   203 MSSFVTTLAGIPNVRITRCGYTGEDGVEISVASSQAQKLTESLLESGVLKLAGLGARDSLRLEAG 267
            ..|......|: ....:|.|||||||.|:|:....:.....:||....::..||||||:||||||
pombe   193 GQSAYVDFKGV-KCLFSRSGYTGEDGFEVSIPEEVSVDFASTLLADTRVRPIGLGARDTLRLEAG 256

  Fly   268 LCLYGSDIDSKTTPVEAALAWLVTKRRRTTRDFPGADVILGQLKEGVSRRRVGLQMLGTKPPPAR 332
            :||||||||..|:|||.:|:|::.||||....|.|:..||.:||:|.||||||..:   :..|||
pombe   257 MCLYGSDIDDTTSPVEGSLSWIIGKRRRKEGGFVGSSRILKELKDGPSRRRVGFIV---EKVPAR 318

  Fly   333 SGVAIFSQGQQVGQVTSGCPSPSAGRNIAMGYVAENLKAPGTKVEFKVRDKLYEAEVTKMPFVKA 397
            .|.|:...|.:|||||||||||:.|:||||||::..|...||....|||:||:.|:|.:||||:.
pombe   319 HGSAVEVDGVEVGQVTSGCPSPTLGKNIAMGYISTGLHQVGTPAHIKVRNKLHPAQVVRMPFVET 383

  Fly   398 NYY 400
            :||
pombe   384 HYY 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	PLN02319	3..403	CDD:177953	173/393 (44%)
		GCV_T	31..288	CDD:279857	105/256 (41%)
		GCV_T_C	298..392	CDD:285832	47/93 (51%)
gcv1	NP_594015.1	PLN02319	17..387	CDD:177953	167/381 (44%)
		GCV_T	28..277	CDD:279857	105/256 (41%)
		GCV_T_C	287..378	CDD:285832	47/93 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	201	1.000	Domainoid score	I655
eggNOG	1	0.900	-	-		E1_COG0404
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H409
Inparanoid	1	1.050	315	1.000	Inparanoid score	I561
OMA	1	1.010	-	-		QHG53675
OrthoFinder	1	1.000	-	-		FOG0004170
OrthoInspector	1	1.000	-	-		oto102040
orthoMCL	1	0.900	-	-		OOG6_101103
Panther	1	1.100	-	-	LDO	PTHR43757
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R483
SonicParanoid	1	1.000	-	-		X2922
TreeFam	1	0.960	-	-
	14	13.860