DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6415 and Dmgdh

DIOPT Version :9

Sequence 1:	NP_609441.1	Gene:	CG6415 / 34474	FlyBaseID:	FBgn0032287	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_038957650.1	Gene:	Dmgdh / 245961	RGDID:	620453	Length:	884	Species:	Rattus norvegicus

Alignment Length:	336	Identity:	92/336 - (27%)
Similarity:	162/336 - (48%)	Gaps:	20/336 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RQVGSIFDVSHMLQSRIFGKDAAACLESVCTADILGTPE-GSGSLTVFTNEAGGILDDLIVNKVS 129
            ::|| :.|:|...:..|.|:|:...|:.:| |:::  |: |..:::......|.:..:|.|:..|
  Rat   547 QRVG-VIDLSPFGKFNIKGQDSTQLLDHLC-ANVI--PKVGFTNISHMLTPRGRVYAELTVSHQS 607

  Fly   130 EKELYVVSNAAMKEQDM-GIMKTAVDNFKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTG 193
            ..|..:::.:..:..|: .|.:.||..    |.||.|..:|. :..::.|.||...:.|.||.:.
  Rat   608 PGEFLLITGSGSELHDLRWIEEAAVRG----GYDVEIRNITD-ELGVLGVAGPYARRVLQKLTSE 667

  Fly   194 KASLDQLYFMSSFVTTLAGIPNVRITRCGYTGEDGVEISVASSQAQKLTESLLESGV---LKLAG 255
            ..|.|...|:.:....::.|| |...|..||||.|.|:......:..|.|.::.:|.   :...|
  Rat   668 DLSDDVFKFLQTKSLKISDIP-VTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFG 731

  Fly   256 LGARDSLRLEAGLCLYGSDIDSKTTPVEAALAWLVTKRRRTTRDFPGADVILGQLK-EGVSRRRV 319
            ..|.::||||.....:||:::..|.|:||.|.:.:  :.....:|.|... |.|:| :|:.||.|
  Rat   732 TYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFI--KLNKPANFTGKQA-LKQIKAKGLKRRLV 793

  Fly   320 GLQMLGTKPPPARSGVAIFSQGQQVGQVTSGCPSPSAGRNIAMGYVAENLKAPGTKVEFKVRDKL 384
            .| .|.|.........:::.:|:.:|..|||..|.|..:::|..||...|...|.:||.::..|.
  Rat   794 CL-TLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKN 857

  Fly   385 YEAEVTKMPFV 395
            |.|.:.:.|.|
  Rat   858 YPATIIQEPLV 868

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	PLN02319	3..403	CDD:177953	92/336 (27%)
		GCV_T	31..288	CDD:279857	61/226 (27%)
		GCV_T_C	298..392	CDD:285832	29/94 (31%)
Dmgdh	XP_038957650.1	DadA	67..455	CDD:223737
		FAO_M	437..492	CDD:406692
		GcvT	508..877	CDD:223481	92/336 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810