DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6415 and pdpr-1

DIOPT Version :9

Sequence 1:	NP_609441.1	Gene:	CG6415 / 34474	FlyBaseID:	FBgn0032287	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_492730.2	Gene:	pdpr-1 / 172922	WormBaseID:	WBGene00013718	Length:	855	Species:	Caenorhabditis elegans

Alignment Length:	347	Identity:	99/347 - (28%)
Similarity:	163/347 - (46%)	Gaps:	42/347 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RQVGSIFDVSHMLQSRIFGKDAAACLESVCTADILGTPEGSGSLTVFTNEAGGILDDLIVNKVSE 130
            |:...:.|:|...:..|.|:||...|:.:|:|:: ..|.|:...|...::.||.:.|..::::.|
Worm   507 RERVGLMDMSSFSKYDITGEDAVEYLQFLCSANV-DEPIGTTVYTGMQHQKGGYVTDCTLSRLGE 570

  Fly   131 KELYVVSNAAMKEQDMGIMKTAVDNFKSQGKDVSIEFLTPADQSLVAVQGPQVAKELSKLLTGKA 195
            |:.::|:....:|:.:..||......|::   |.::.:|.|..:|..: ||. ::.|...:||.:
Worm   571 KKFFMVAPTIQQERVLVWMKKWQAILKAR---VHVQDVTGAYTALDLI-GPS-SRYLMGDITGLS 630

  Fly   196 SLDQLYFMSS--FVT---------TLAGIPNVRITRCGYTGEDGVEISVASSQAQKLTESLLESG 249
                   |||  |.|         ...||..:.:|.|   ||.|..|.|.:..||.:.|.:|::|
Worm   631 -------MSSNDFPTFRCQEINIGMATGIRAISVTHC---GELGWVIYVPNEVAQNVYEKILDAG 685

  Fly   250 ---VLKLAGLGARDSLRLEAGLCLYGSDIDSKTTPVEAALAWLVTKRRRTTRDFPGADVILGQLK 311
               .|:.||......||:|.....:|.||::..||||....:.|..:    :||.|...:..|::
Worm   686 KEYSLQHAGYYTLRQLRIEKFYVYWGQDINATVTPVECGRLFRVDFK----KDFIGKKALEEQVE 746

  Fly   312 EGVSRRRVGLQMLG----TKPPPARSGVAIFSQGQQVGQVTSGCPSPSAGRNIAMGYVAENLKAP 372
            .|||:|.|.|.:.|    |.|.| :.|..|...|:.||..||.....:.|..:.:||| || |..
Worm   747 RGVSKRFVQLLVDGHDKETDPWP-QGGETILKDGRAVGLTTSAAYGFTLGCQVCIGYV-EN-KEF 808

  Fly   373 GTKVEFKVRDKLYEAEVTKMPF 394
            |...|| |....:|.::....|
Worm   809 GVSPEF-VSSGHFEIDIAGKRF 829

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6415	NP_609441.1	PLN02319	3..403	CDD:177953	99/347 (29%)
		GCV_T	31..288	CDD:279857	64/235 (27%)
		GCV_T_C	298..392	CDD:285832	33/97 (34%)
pdpr-1	NP_492730.2	DAO	23..387	CDD:279590
		NAD_binding_8	28..>54	CDD:290186
		FAO_M	394..445	CDD:292961
		GcvT	439..833	CDD:223481	99/347 (29%)
		GCV_T	449..724	CDD:279857	64/232 (28%)
		GCV_T_C	733..833	CDD:285832	34/101 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810