DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7300 and H43E16.1

DIOPT Version :9

Sequence 1:	NP_001188789.2	Gene:	CG7300 / 34472	FlyBaseID:	FBgn0032286	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_495358.1	Gene:	H43E16.1 / 174101	WormBaseID:	WBGene00019273	Length:	1203	Species:	Caenorhabditis elegans

Alignment Length:	816	Identity:	191/816 - (23%)
Similarity:	337/816 - (41%)	Gaps:	127/816 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SVLNQAANGILGAASTGANVVHSAGSAAASHGAQAANAVLGAAGSGVDAVHSAGSTAAAHGAQAV 126
            |.|.|.::.::.|...||  :.|..........|..|:|:.:..|....||:|        .||.
Worm   272 SALRQGSDNMVVAIGNGA--ISSTSDLGTMPTDQNVNSVITSDNSTYSDVHTA--------PQAC 326

  Fly   127 NGIL-----GAASTGANVVHSAGSAAANHGAQAANAVLGAAGSGVDAVHSAGSTAAAHGAQAVNG 186
            |..:     ...||.|.||.:..|:     |.|:.||:...........:..|...:...|||..
Worm   327 NKNIIQTDCPVCSTAAPVVCTTASS-----APASTAVVTTTMPVTTVQTTVTSIGTSTSPQAVVT 386

  Fly   187 ILGAASTGANVVHSAGSAAANHGAQAAHGVLGATGSGVDAIHSAGSTAAAHGAQAVNGILGVAGT 251
            ..|..:|.|.:..|:.:..:....|.:...:..|..||.:..:..:|:.|......|.:  .:..
Worm   387 TTGNPTTTAQLSSSSKTLTSTQTTQGSPSTVSQTTPGVSSASTGMTTSQASLRSTQNSV--TSTP 449

  Fly   252 GANVVHSAGSTAASYGAHAAHGVLGAAATGVNAVHSAGVT--AADEVHKASSQHSGSGSASLGVG 314
            |:..|.|..:..::.||.|:..  ..:.|...|:.|:.||  |:..:...|||.|.|.::|....
Worm   450 GSFTVTSTPTITSTQGAMASSS--SNSPTSTQAISSSTVTTVASSTIAPTSSQESSSIASSSAPS 512

  Fly   315 H----LNIQTSG--NSGSKTNTAHLTIGTSGVSGSSDLHHSAGSATVN--AANAVLNAAEAGAAG 371
            .    :.:.|:.  :||..|:|...|||.....|||.:..:.|:::..  .:.|..::...|:..
Worm   513 QSTTVITVSTTATVSSGQSTSTFGTTIGQGSSFGSSTIQTTQGTSSFAPIPSTAGSSSQTPGSMS 577

  Fly   372 STGAAHGAQVVNGVLGVAGTGANVIHSAGTITAAHGAQAADTVASGVVNGATSGSGANSGHLSIG 436
            |||...| |:.:.....|.|      |.|||....|..:..::::.|          |||..:||
Worm   578 STGTTVG-QMSSSFQPTAPT------SLGTIMTTPGTSSIPSISTSV----------NSGSSTIG 625

  Fly   437 SSGISG-SSSGSLGNAKITGSSSTGAHHTGSVQAGSAKITAGHGKIETSGSNSGTAGHINVDATG 500
            |:.... |||.|:|.:.   |.||    .||....:..:|:. ....|..::|||...:......
Worm   626 STVTQAPSSSTSMGPSP---SQST----AGSTMTSAPPVTSS-SSANTGSTSSGTTVSVQTTQVS 682

  Fly   501 ASEKKTSSSYHKSESTMVSSGHSSTYSSKTE------------SSKFSAGQSHIS----SGSATI 549
            ::....:||..:..||...||.||:..|...            ||:.:|.|...|    :.|:|:
Worm   683 STTSPVASSSSQMTSTQQPSGSSSSIGSTVNQGSSSVTTQPPASSRSTASQGSSSAQPIASSSTM 747

  Fly   550 GASGTHAASAHIKTENKKVESSGSSSMHAGSGSASIGAGH--------LNVQSAGTTGSSEAASN 606
            |::...::.....:......|:|::|..:..||:::|:..        .|..|.|:|.:::.||:
Worm   748 GSTAGSSSPQPTASSTSVPSSTGATSSGSTVGSSTMGSTQSSLPSSTMTNTGSTGSTVTNQLASS 812

  Fly   607 HASIGVGHLNIGATDSASKGSSALGSSGHLSIGSAGISGSAGSGASG----------SHTGSAHI 661
             ::.|.......|:.:|:.|||..|.:...:.||:....::.:|::|          |.:||:..
Worm   813 -STYGASSTEPIASSTANPGSSTSGQTAVTTQGSSSTQTNSNTGSTGSTVTNPPVSSSTSGSSST 876

  Fly   662 KTEHKKVESSGSS----SLHTGSGSASIEAGHLNIQSAGSTGSS-------QAASIGVGHLSIGS 715
            :.......:.|||    ::.|..||:|.:..    .:.|||||:       .:.|.......|.|
Worm   877 QPIASSTANPGSSTSGTTVVTTQGSSSTQTN----PNTGSTGSTVTQPSAFSSTSASSSTQPIAS 937

  Fly   716 TDSASKGSSGTGSSGHLSIGSVGISGSTGSGAGSSKINAGHLSIGTSGNSGSASLGTNGLSIGAN 780
            :.:|:.|||.:|.:         |:.:.||.:..:..|.|..::.|:...||::.|..| |...|
Worm   938 STTANPGSSTSGPT---------IASTQGSSSTQTNSNTGSTTVATTVTQGSSTEGNTG-STTVN 992

  Fly   781 GHNSNTAGSIGLAGAHEAASLAHGVASGILTPAVGS 816
            ..:|:.|.::       |:|.::.|:|....|...|
Worm   993 SQSSSVASTV-------ASSTSNIVSSTSQAPTCAS 1021

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7300	NP_001188789.2	None
H43E16.1	NP_495358.1	rad2	<76..>260	CDD:273166
		PHA03307	556..>908	CDD:223039	86/381 (23%)
		FSA_C	<933..1022	CDD:287455	27/106 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000