DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SAMD7 and samd7

DIOPT Version :9

Sequence 1:	NP_001291295.1	Gene:	SAMD7 / 344658	HGNCID:	25394	Length:	446	Species:	Homo sapiens
Sequence 2:	XP_005171361.1	Gene:	samd7 / 563729	ZFINID:	ZDB-GENE-070912-549	Length:	527	Species:	Danio rerio

Alignment Length:	481	Identity:	165/481 - (34%)
Similarity:	245/481 - (50%)	Gaps:	60/481 - (12%)

- Green bases have known domain annotations that are detailed below.

Human     1 MAVNPLLTPTGQQTIPLIPSPFGPPTVDRDVL-PSTVAPTDPRQFCVPSQFGSSVLPNTNMANVL 64
            ||:.|.:...|||.:..:|:.|.|..::|::: |:.:...|.||..:.:..|..:.||   :||:
Zfish    49 MAMAPQILAQGQQRLQGVPAQFDPRFMERELVPPADMVSADARQIHMGAHLGQQLPPN---SNVI 110

Human    65 SSRIYPGWG--ILPPESIKAVARRNEMIQRHHTARTEMEMYAIYQQRRMEKINPKGLAGLGIPFL 127
            ..|.|||.|  .|..||::.||||.|:|.:.:.||  |||.||..|:.:|..:.|||..:..|.:
Zfish   111 PGRGYPGTGYNFLQTESMETVARRQELIHKQNIAR--MEMNAILHQKELENAHQKGLISIENPMM 173

Human   128 YGSSVPAAPAAYHGRSMLPAG-DLHFHRSTLRNLQGNPMLAATA-PHFEESWGQRCRRLRKNTGN 190
            | ..:...|.|:.||..||.| |:..||:.|.:|..|.:|.::. |.......:|.||..:.|.|
Zfish   174 Y-QGIQPNPMAFRGRQRLPDGHDVFVHRTALEDLHANSLLMSSPYPPISTLQRERGRRTGRRTTN 237

Human   191 QKALDSDAESSKSQAEEKILGQTHAVPYEEDHYAKDPDIEAPSNQKSSETNEKPTTALANTCG-- 253
            .|:.||:....|.|:|||.:.|:......|:..|:....:|.|::......|...::..:..|
Zfish   238 HKSSDSNITLPKGQSEEKNIEQSPGAASGEEKEAEGKGSDATSSKPHQTKAETELSSGGSRKGFK 302

Human   254 ELEPTHRKPWGSHTTTLKAKAWDDGKEEASEQIFATCD-EKNGVC---------PPVPRPSLPGT 308
            |.||..||         ...:..:|..|.|....:|.| :.:..|         |....| |.|.
Zfish   303 EGEPGIRK---------ACISGQEGCAEVSNCNASTSDKDMSNPCSAFQDKFLYPSTSGP-LTGM 357

Human   309 HALVTIGGN----------------LSLDEDIQKWTVDDVHSFIRSLPGCSDYAQVFKDHAIDGE 357
            ..::.:.||                :|..|||:|||||||:|||..:|.|::|||.||:|.||||
Zfish   358 PYMLPVPGNGLLPLGPPNMFLNGEEMSSSEDIRKWTVDDVYSFISEIPSCAEYAQTFKEHMIDGE 422

Human   358 TLPLLTEEHLRGTMGLKLGPALKIQSQVSQHVGSMFYK-KTLSFPI-------RQAFDQPADTSP 414
            |||||||:||..|:||||||||||:||:|:.:|:|||. ..|..|:       .::.|:.:|.|.
Zfish   423 TLPLLTEDHLLDTLGLKLGPALKIRSQLSRRLGNMFYNMMNLPLPVSGLQPPPEKSVDRSSDISS 487

Human   415 LLDPNSWSDTMNIFCPQDTIIPKGIE 440
            .|:.||   ...:..|:||...|..|
Zfish   488 PLNCNS---VEMLSSPRDTDALKAAE 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SAMD7	NP_001291295.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..207		7/19 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	225..277		9/53 (17%)
		SAM_Samd7,11	324..391	CDD:188978	46/66 (70%)
samd7	XP_005171361.1	SAM_Samd7,11	389..456	CDD:188978	46/66 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194337174
Domainoid	1	1.000	119	1.000	Domainoid score	I22679
eggNOG	1	0.900	-	-		E1_KOG3829
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I10710
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG40594
OrthoDB	1	1.010	-	-		D213068at7742
OrthoFinder	1	1.000	-	-		FOG0012422
OrthoInspector	1	1.000	-	-		oto42786
orthoMCL	1	0.900	-	-		OOG6_120216
Panther	1	1.100	-	-	LDO	PTHR12247
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R11891
SonicParanoid	1	1.000	-	-		X10393
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	17	17.300