Protein Alignment SAMD7 and samd7

DIOPT Version :10

• Sequence 1: NP_872416.1
• Gene: SAMD7 / 344658
• HGNCID: 25394
• Length: 446
• Species: Homo sapiens
• Sequence 2: XP_009296916.2
• Gene: samd7 / 563729
• ZFINID: ZDB-GENE-070912-549
• Length: 527
• Species: Danio rerio
• Alignment Length: 481
• Identity: 164/481 - (34%)
• Similarity: 244/481 - (50%)
• Gaps: 60/481 - (12%)

Human     1 MAVNPLLTPTGQQTIPLIPSPFGPPTVDRDVL-PSTVAPTDPRQFCVPSQFGSSVLPNTNMANVL 64
            ||:.|.:...|||.:..:|:.|.|..::|::: |:.:...|.||..:.:..|..:.||   :||:
Zfish    49 MAMAPQILAQGQQRLQGVPAQFDPRFMERELVPPADMVSADARQIHMGAHLGQQLPPN---SNVI 110

Human    65 SSRIYPGWG--ILPPESIKAVARRNEMIQRHHTARTEMEMYAIYQQRRMEKINPKGLAGLGIPFL 127
            ..|.|||.|  .|..||::.||||.|:|.:.:.||  |||.||..|:.:|..:.|||..:..|.:
Zfish   111 PGRGYPGTGYNFLQTESMETVARRQELIHKQNIAR--MEMNAILHQKELENAHQKGLISIENPMM 173

Human   128 YGSSVPAAPAAYHGRSMLPAG-DLHFHRSTLRNLQGNPMLAATA-PHFEESWGQRCRRLRKNTGN 190
            | ..:...|.|:.||..||.| |:..||:.|.:|..|.:|.::. |.......:|.||..:.|.|
Zfish   174 Y-QGIQPNPMAFRGRQRLPDGHDVFVHRTALEDLHANSLLMSSPYPPISTLQRERGRRTGRRTTN 237

Human   191 QKALDSDAESSKSQAEEKILGQTHAVPYEEDHYAKDPDIEAPSNQKSSETNEKPTTALANTCG-- 253
            .|:.||:....|.|:|||.:.|:......|:..|:....:|.|::......|...::..:..|
Zfish   238 HKSSDSNITLPKGQSEEKNIEQSPGAASGEEKEAEGKGSDATSSKPHQTKAETELSSGGSRKGFK 302

Human   254 ELEPTHRKPWGSHTTTLKAKAWDDGKEEASEQIFATCD-EKNGVC---------PPVPRPSLPGT 308
            |.||..||         ...:..:|..|.|....:|.| :.:..|         |....| |.|.
Zfish   303 EGEPGIRK---------ACISGQEGCAEVSNCNASTSDKDMSNPCSAFQDKFLYPSTSGP-LTGM 357

Human   309 HALVTIGGN----------------LSLDEDIQKWTVDDVHSFIRSLPGCSDYAQVFKDHAIDGE 357
            ..::.:.||                :...|||:|||||||:|||..:|.|::|||.||:|.||||
Zfish   358 PYMLPVPGNGLLPLGPPNMFLNGEEMPSSEDIRKWTVDDVYSFISEIPSCAEYAQTFKEHMIDGE 422

Human   358 TLPLLTEEHLRGTMGLKLGPALKIQSQVSQHVGSMFYK-KTLSFPI-------RQAFDQPADTSP 414
            |||||||:||..|:||||||||||:||:|:.:|:|||. ..|..|:       .::.|:.:|.|.
Zfish   423 TLPLLTEDHLLDTLGLKLGPALKIRSQLSRRLGNMFYNMMNLPLPVSGLQPPPEKSVDRSSDISS 487

Human   415 LLDPNSWSDTMNIFCPQDTIIPKGIE 440
            .|:.||   ...:..|:||...|..|
Zfish   488 PLNCNS---VEMLSSPRDTDALKAAE 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAMD7	NP_872416.1	Required for localization to nuclear polycomb bodies. /evidence=ECO:0000250|UniProtKB:Q8C8Y5	94..168		28/74 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..207		7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..277		9/53 (17%)
		SAM_Samd7,11	324..391	CDD:188978	46/66 (70%)
samd7	XP_009296916.2	None